ID Q22MS5_TETTS Unreviewed; 535 AA.
AC Q22MS5;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 24-JAN-2024, entry version 80.
DE SubName: Full=WD domain, G-beta repeat protein {ECO:0000313|EMBL:EAR86562.1};
GN ORFNames=TTHERM_00030480 {ECO:0000313|EMBL:EAR86562.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR86562.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GG662720; EAR86562.1; -; Genomic_DNA.
DR RefSeq; XP_976945.1; XM_971852.1.
DR AlphaFoldDB; Q22MS5; -.
DR EnsemblProtists; EAR86562; EAR86562; TTHERM_00030480.
DR GeneID; 7828676; -.
DR KEGG; tet:TTHERM_00030480; -.
DR eggNOG; ENOG502RWMU; Eukaryota.
DR HOGENOM; CLU_509532_0_0_1; -.
DR InParanoid; Q22MS5; -.
DR OMA; QYINEIM; -.
DR OrthoDB; 5690070at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44675:SF1; P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR44675; PAK1 INTERACTING PROTEIN 1; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 236..276
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 409..450
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT COILED 84..133
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 178..205
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 535 AA; 62084 MW; 731A8D80B8BE6D3A CRC64;
MLNCQLSKIK NLKELKCLIP GHYQQVKNIV CLDKDCENKG LICIYCLQNL HCNHKFMGIE
QYINEIMKFR QQEYQYSHHI ECLRKQLNKR YQSLQLKITD LASNLEILTH QIKQKYEKDL
DNIYNMSEIL RQQQEDFITM QDNEDALSCE TLTKFIDISF KFINYTYDDN ELIKINNYQK
GLSELDIYEN RLDSIEQTIS ESLKEVQMHQ SYLLQEDLKK IENLDISPST YHKKIQQAHI
HIISSMVLIN HNYLYTASHD GYIKMWNTQN LSCMKVLKSS YSKIWLALVY LQGLNCLLGL
TNDNTLNLIN PTTLKVTKRI QIPSSYSSCP LIVQVPGCNN QVAVASGSKV FIIDLITSSV
VHATDTNGYY VYSFDIWTDG NYKYIIYGDK AGKLYSNEIK TKTEMPPIDK AHEEKVVDVK
VLKDSNYVIT ASTDKRIKVW KMPVMQYVGT WEVKGFVDAI VSIQNMLVVK QRDVDKLFLI
YKDQKGSCKL RPFVSINTDT VGVFQINELN RSVVSSIFVN GLENLPYSDI VIDFY
//
