ID Q22XT3_TETTS Unreviewed; 300 AA.
AC Q22XT3;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 2.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Ubiquitin carboxy-terminal hydrolase 37 receptor-binding site protein {ECO:0000313|EMBL:EAR90088.2};
GN ORFNames=TTHERM_01005130 {ECO:0000313|EMBL:EAR90088.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR90088.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; GG662802; EAR90088.2; -; Genomic_DNA.
DR RefSeq; XP_001010333.2; XM_001010333.3.
DR AlphaFoldDB; Q22XT3; -.
DR STRING; 312017.Q22XT3; -.
DR EnsemblProtists; EAR90088; EAR90088; TTHERM_01005130.
DR GeneID; 7834282; -.
DR KEGG; tet:TTHERM_01005130; -.
DR eggNOG; KOG3037; Eukaryota.
DR HOGENOM; CLU_1047510_0_0_1; -.
DR InParanoid; Q22XT3; -.
DR OMA; SNQRHFF; -.
DR OrthoDB; 5483381at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.2020.20; -; 1.
DR Gene3D; 2.30.29.70; Proteasomal ubiquitin receptor Rpn13/ADRM1; 1.
DR InterPro; IPR044867; DEUBAD_dom.
DR InterPro; IPR006773; Rpn13/ADRM1.
DR InterPro; IPR044868; Rpn13/ADRM1_Pru.
DR InterPro; IPR038633; Rpn13/ADRM1_Pru_sf.
DR InterPro; IPR032368; RPN13_DEUBAD.
DR InterPro; IPR038108; RPN13_DEUBAD_sf.
DR PANTHER; PTHR12225; ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN; 1.
DR PANTHER; PTHR12225:SF0; PROTEASOMAL UBIQUITIN RECEPTOR ADRM1; 1.
DR Pfam; PF04683; Rpn13_ADRM1_Pru; 1.
DR Pfam; PF16550; RPN13_C; 1.
DR PROSITE; PS51916; DEUBAD; 1.
DR PROSITE; PS51917; PRU; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000313|EMBL:EAR90088.2};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Receptor {ECO:0000313|EMBL:EAR90088.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168}.
FT DOMAIN 3..116
FT /note="Pru"
FT /evidence="ECO:0000259|PROSITE:PS51917"
FT DOMAIN 192..300
FT /note="DEUBAD"
FT /evidence="ECO:0000259|PROSITE:PS51916"
FT REGION 126..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 300 AA; 34167 MW; 756346A9B1929024 CRC64;
MSLDFVKEYS FKAGIMNLDP TTKKVTADKR KGTVKIGCTL EGEKPFTWTP EGATEPEFEY
AVMQSDASLE LSKQMKRVVV LRFQCDESRY FFWLQEKDAS KDAEIVSRVQ DIIDFDIEQL
MIDESSSVSE PQQSLSQQSS SQSQPQPAQQ GQPNLMNANL FGAQFQDMFQ NMLNQRGGNN
NPMMQQLLQQ YQQRQRDTPN FFEVLTKESL MELANDEEVQ KELIQHLPEG QQDVQNLKEN
LISPQFQQAL ESLEKALNSN EGGAVLASLG LDQSNFMETL DGSDSFYKAI IKWAESQKKQ
//
