ID Q23BT7_TETTS Unreviewed; 548 AA.
AC Q23BT7;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 24-JAN-2024, entry version 88.
DE SubName: Full=Tetratricopeptide repeat protein {ECO:0000313|EMBL:EAR94031.1};
GN ORFNames=TTHERM_00227450 {ECO:0000313|EMBL:EAR94031.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR94031.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662718; EAR94031.1; -; Genomic_DNA.
DR RefSeq; XP_001014276.1; XM_001014276.1.
DR AlphaFoldDB; Q23BT7; -.
DR STRING; 312017.Q23BT7; -.
DR EnsemblProtists; EAR94031; EAR94031; TTHERM_00227450.
DR GeneID; 7831614; -.
DR KEGG; tet:TTHERM_00227450; -.
DR eggNOG; KOG2084; Eukaryota.
DR HOGENOM; CLU_497423_0_0_1; -.
DR InParanoid; Q23BT7; -.
DR OMA; NLQHWGF; -.
DR OrthoDB; 5377at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR47643; TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710); 1.
DR PANTHER; PTHR47643:SF2; TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710); 1.
DR Pfam; PF12895; ANAPC3; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00317; SET; 1.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT REPEAT 202..235
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 345..525
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 548 AA; 64004 MW; 1C44E7931034B8F8 CRC64;
MKKNNEDQLK SFFEFGKFMT QNKDQFSSIA QNMLSTKQLL QIKQKATIQQ EIEEQRNYIS
SHSHNIKQTV ADQISLANKC SLGLEKLKKI YLEDLVVNKP MENCVVYVKT FCKPSKMNAI
NLGIEDEKSN YIHISLYNSE KSNCDLKYLD QKYPLNLNLA IKNPYMKMNA VGHVFLRNDN
PENILFLNSN QQQDNDKQLK EFNSLKQKGN ELFSQKQYKQ AIEFYLKAIQ FASSNEEKII
ATSNISQALI CQNNYQKAIF YADRALELDQ THQKSLFRKA TSLVGLYDFE KALKVFEQLK
PNQECEKHME ECKYKLNKQK NGFTQDEIAE IIQKKQGQKL VNFVGNIEIR RTQKMGRGVF
ATKSIRKNEV IAVCEFVQAK INKGELLVEY IDTENLAVNL NSQYFIREQL IMEMQENFYL
RKVLSYLYRG EINKDYQIPN LKEVFVKKYY QEGLDDKIEL TAEDVSNIVN YNTFGSRNST
QLIMLASFFN HKNVSDVLLI DVEDKVVIVS QREIQKDEEI FITYINQSDK DKEQVAKDLQ
KWGITEVN
//
