ID Q23F52_TETTS Unreviewed; 456 AA.
AC Q23F52;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 24-JAN-2024, entry version 77.
DE RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};
GN ORFNames=TTHERM_00383610 {ECO:0000313|EMBL:EAR95301.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR95301.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU000441}.
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DR EMBL; GG662706; EAR95301.2; -; Genomic_DNA.
DR RefSeq; XP_001015546.2; XM_001015546.2.
DR AlphaFoldDB; Q23F52; -.
DR STRING; 312017.Q23F52; -.
DR EnsemblProtists; EAR95301; EAR95301; TTHERM_00383610.
DR GeneID; 7838034; -.
DR KEGG; tet:TTHERM_00383610; -.
DR HOGENOM; CLU_025068_0_1_1; -.
DR InParanoid; Q23F52; -.
DR OrthoDB; 642531at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0046912; F:acyltransferase activity, acyl groups converted into alkyl on transfer; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Transferase {ECO:0000256|RuleBase:RU000441}.
SQ SEQUENCE 456 AA; 53467 MW; F707DB21A9FA3712 CRC64;
MIWINSICPF SINRLNGVVK QEIKNKKLYC GDDVISRLRI GMIQLVRFCN IRHCSEKRQI
QMEYFQQFLI TLQEINTFHV LLEKQQKQKN KKNNKKRKKE KEQRKINFER IKEKETFAKM
ERISEINQQV NKNDVNKKDT LTITDRKGNT FELKIHNNEF IQANDLLKVG LKDEGVLRSY
DPGYMNTICC TSKISYIDGD KGILEYRGYP IEQLAEKSNF LEVAFLLIYG ELPTPSQFQI
WKNKIQTHTF VHQDINQMMK SFRYDAHPMG MLVSTIAATS TFHPEANPAL SGQNIYEDST
VRNKQIHRIL GNITTIAANC YRHRIGRSHN KPHPKLDYVE NFLYMLDRLN ENKYLPHPKL
VKALDILFIL HAEHELNCST AAIRHLCSSG VDVYSCISGA AAALYGPKHV IIKFQFIFFL
TINKLKYLNF QQFSYKNYKA KVKKAFLNKE YENMNW
//
