ID Q23QV6_TETTS Unreviewed; 538 AA.
AC Q23QV6;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=MAC/perforin domain protein {ECO:0000313|EMBL:EAR98782.1};
GN ORFNames=TTHERM_00249770 {ECO:0000313|EMBL:EAR98782.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAR98782.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662647; EAR98782.1; -; Genomic_DNA.
DR RefSeq; XP_001019027.1; XM_001019027.1.
DR AlphaFoldDB; Q23QV6; -.
DR STRING; 312017.Q23QV6; -.
DR EnsemblProtists; EAR98782; EAR98782; TTHERM_00249770.
DR GeneID; 7843215; -.
DR KEGG; tet:TTHERM_00249770; -.
DR eggNOG; ENOG502S7UT; Eukaryota.
DR HOGENOM; CLU_526299_0_0_1; -.
DR InParanoid; Q23QV6; -.
DR OrthoDB; 213867at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR45742; COMPLEMENT COMPONENT C6; 1.
DR PANTHER; PTHR45742:SF8; MACPF DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01823; MACPF; 1.
DR PROSITE; PS51412; MACPF_2; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..538
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004201800"
FT DOMAIN 33..361
FT /note="MACPF"
FT /evidence="ECO:0000259|PROSITE:PS51412"
SQ SEQUENCE 538 AA; 60476 MW; 9DE63F683EACDF64 CRC64;
MKPTKTKIKS ILIITLIISC IKCNDISDTL QWNDSINTQS IQYIPNVQYL GQGYNIFTSN
PHSSQGLDPG YKNIAAINLT YTDNLWQNVN PERTYFVPNG VFLSQQKSCT MSFTARQVAS
MMDYTSSLEA SVSIKGTFFG GRFRASVDYQ DMQNDMESGE YQYIVSHSSC SVFQLDLIDS
PTYHAQFTND ILMDFQNLIS IQGNSSNTEA NAYYDFFDKW GTHVVSSVNL GSLFGYKFQL
LTSDIQSMNN QGIDVSASAT IFNVRGRTNT QIEQNNLDNF SQSIQKWTSY SIGATPDVNN
DPANWASQTL TKPMPIKSSI TPYHEALNIF TQGNNSILQS SQILQLYYKL RLYGNSYCSQ
RLLPNGQIDQ CNSNSQSDYN FSQQEQTVTY YDVSLLDITR TQIAAYYQNA TTFNTQLQLS
PIENTIGYRF FFKNNNQILN GQVTYYVSIV ATAGNNMCLV GNPTLGEPAT ISGCPNNDNA
TFSYIAYDDN IFSLQFKSDP TKCLGFDSQG ILRTMVTDSC FECQVIELIQ NTQTKKNS
//
