ID Q241L6_TETTS Unreviewed; 504 AA.
AC Q241L6;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Transmembrane protein, putative {ECO:0000313|EMBL:EAS02554.2};
GN ORFNames=TTHERM_00630740 {ECO:0000313|EMBL:EAS02554.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS02554.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
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DR EMBL; GG662532; EAS02554.2; -; Genomic_DNA.
DR RefSeq; XP_001022799.2; XM_001022799.2.
DR AlphaFoldDB; Q241L6; -.
DR EnsemblProtists; EAS02554; EAS02554; TTHERM_00630740.
DR GeneID; 7830873; -.
DR KEGG; tet:TTHERM_00630740; -.
DR HOGENOM; CLU_2008529_0_0_1; -.
DR InParanoid; Q241L6; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR027038; RanGap.
DR PANTHER; PTHR24113:SF12; F-BOX DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24113; RAN GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF13516; LRR_6; 5.
DR SMART; SM00368; LRR_RI; 8.
DR SUPFAM; SSF52047; RNI-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Transmembrane {ECO:0000256|SAM:Phobius, ECO:0000313|EMBL:EAS02554.2};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 306..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 504 AA; 54634 MW; E5167C53C3C090DC CRC64;
MKQFFLQNLK SQNQLGDERA SDLYSALANC INLSNLTLIL YENQIGDEGA SGLGSALANC
IKLSNLTLDL SYNKIGNEGA SGLGSALTNC INLSNLTLYL SNNQIGVMGA SGLGSALANC
INLSNLALCL INNQIGVMGA SGLGSALANC INLSNLTLYL IKNQIGDEGA SGLGSALANC
INLSNLKLQL NYNQIGVMGS SGLCSALANC INLSNLKLIL GYNQIGVMGA SGLCSALANC
INLSNLTLNL SNNQIGVMGA SGLGSALANC IKLQNLTLNL SNNQIGDEGA SGLGSALANC
IQILNLTLNL SSFFFFFLLC FLFFQQLNWC TYIHTYSHMV TCTRDRALYI ITYTLLLYVY
QFIYIQLWVI YQKGRVTYTL MAFLLIFHDL TTHYARFPFV FQIFCSEWGL LFTTYQIWPF
PPTKETAGNI HIFYMEFFEI KGAVQDSNPR YHCQDPPTRP LESLSPSQIG VMGASGLGSA
LANCINLSNL TLNLRQKQFI CFGF
//
