ID   Q248F0_TETTS            Unreviewed;       528 AA.
AC   Q248F0;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 2.
DT   27-MAR-2024, entry version 59.
DE   RecName: Full=Phospholipase B-like {ECO:0000256|RuleBase:RU364138};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU364138};
GN   ORFNames=TTHERM_00532170 {ECO:0000313|EMBL:EAS04095.2};
OS   Tetrahymena thermophila (strain SB210).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS04095.2, ECO:0000313|Proteomes:UP000009168};
RN   [1] {ECO:0000313|Proteomes:UP000009168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX   PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA   Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA   Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA   Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA   Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA   Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA   Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA   Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA   Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA   Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA   Hamilton E.P., Orias E.;
RT   "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT   model eukaryote.";
RL   PLoS Biol. 4:1620-1642(2006).
CC   -!- FUNCTION: Putative phospholipase. {ECO:0000256|RuleBase:RU364138}.
CC   -!- SIMILARITY: Belongs to the phospholipase B-like family.
CC       {ECO:0000256|ARBA:ARBA00007835, ECO:0000256|RuleBase:RU364138}.
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DR   EMBL; GG662455; EAS04095.2; -; Genomic_DNA.
DR   RefSeq; XP_001024340.2; XM_001024340.3.
DR   AlphaFoldDB; Q248F0; -.
DR   EnsemblProtists; EAS04095; EAS04095; TTHERM_00532170.
DR   GeneID; 7830939; -.
DR   KEGG; tet:TTHERM_00532170; -.
DR   eggNOG; KOG3774; Eukaryota.
DR   HOGENOM; CLU_027106_4_0_1; -.
DR   InParanoid; Q248F0; -.
DR   OMA; SVPCWMR; -.
DR   OrthoDB; 180150at2759; -.
DR   Proteomes; UP000009168; Unassembled WGS sequence.
DR   GO; GO:0004620; F:phospholipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.60.30; -; 1.
DR   InterPro; IPR007000; PLipase_B-like.
DR   PANTHER; PTHR12370:SF3; PHOSPHOLIPASE B-LIKE 2-RELATED; 1.
DR   PANTHER; PTHR12370; PHOSPHOLIPASE B-RELATED; 1.
DR   Pfam; PF04916; Phospholip_B; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU364138};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW   ECO:0000256|RuleBase:RU364138};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098,
KW   ECO:0000256|RuleBase:RU364138};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU364138}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|RuleBase:RU364138"
FT   CHAIN           21..528
FT                   /note="Phospholipase B-like"
FT                   /evidence="ECO:0000256|RuleBase:RU364138"
FT                   /id="PRO_5011331086"
SQ   SEQUENCE   528 AA;  61254 MW;  FA22B67AEF8C86BF CRC64;
     MKQMSVQVFL LLLSLGITFS AHHIEISPIV GERVTAFSLV DNKTVAKAFY TNALNTTGWT
     ILSIETSKHF SDRDQLYHAG YLEGYLTYDL INYAYYNFLN TVLNGQELNE LQQQFITNQT
     QWIEGQLQQN NQTSQGYWGL VGSLMSQLNG TYDGYVDAMR KNQQQQNILS FNQFYYLTNM
     GDLEDIQNAV LKTNKTEKNC DAYVKLTHND LVCAHSTFNI YSLMLRVYKA YKFEFHNKDV
     KASFQAFSSR PGDLESKDDF YILNNGVVVM ETSLNNYNKS NYDYLHYDSV PCWMRVNLAN
     RLSSNGSEWA QVFSNYRSGT HNNQWIVVDY NQWRAGSRKN IVWMVEESFY LYKPIDVTYQ
     LFSQGYVASY NVPFNQEIFN ITMYQQGYGF NYTNDPRAIE FAQYSKNVST TKDVMKLIRL
     NHNATGDPSD AIAPRFDLLN QGAYTYGAID AKVTNDKLLQ VLQSFMISSP TNDGLPYFSW
     NNWNSVPHQG MPDNYNFDWI NYNYNNQNYT FVEHSSSNQI KNLRVESY
//