ID   Q24CZ1_TETTS            Unreviewed;       909 AA.
AC   Q24CZ1;
DT   18-APR-2006, integrated into UniProtKB/TrEMBL.
DT   16-APR-2014, sequence version 2.
DT   27-MAR-2024, entry version 76.
DE   RecName: Full=Kinase domain protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TTHERM_00713100 {ECO:0000313|EMBL:EAS05617.2};
OS   Tetrahymena thermophila (strain SB210).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS05617.2, ECO:0000313|Proteomes:UP000009168};
RN   [1] {ECO:0000313|Proteomes:UP000009168}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX   PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA   Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA   Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA   Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA   Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA   Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA   Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA   Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA   Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA   Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA   Hamilton E.P., Orias E.;
RT   "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT   model eukaryote.";
RL   PLoS Biol. 4:1620-1642(2006).
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DR   EMBL; GG662338; EAS05617.2; -; Genomic_DNA.
DR   RefSeq; XP_001025862.2; XM_001025862.2.
DR   AlphaFoldDB; Q24CZ1; -.
DR   EnsemblProtists; EAS05617; EAS05617; TTHERM_00713100.
DR   GeneID; 7837446; -.
DR   KEGG; tet:TTHERM_00713100; -.
DR   eggNOG; KOG4308; Eukaryota.
DR   HOGENOM; CLU_324288_0_0_1; -.
DR   InParanoid; Q24CZ1; -.
DR   OrthoDB; 5474824at2759; -.
DR   Proteomes; UP000009168; Unassembled WGS sequence.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR24114; LEUCINE RICH REPEAT FAMILY PROTEIN; 1.
DR   PANTHER; PTHR24114:SF2; PH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13516; LRR_6; 4.
DR   SMART; SM00368; LRR_RI; 9.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          14..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          839..909
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          666..785
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          811..838
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        841..900
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   909 AA;  103889 MW;  601217F8371A091B CRC64;
     MINRDQQFKQ ILSSQKYEGS TNNQNRVSSS TYFPQESQSS SNLMITLQRP QTAKLSQKSF
     TKLPQQGSSS QIKNIDSQRS QKSNPLMKHR NVSSPGHMQK SVKINTKNSI SNYQLGSTKS
     ELTFKSFENI PASSHNIQQN NQITSNTQKG YSPQKTQNTF YQQTGQNQKQ SMMHLQSQNQ
     YKYEELSQIS DSNIMYQEQY DQMNQDVSFQ IQQALNSIKV DQVIKLFESK CKDIKLDVQF
     PQLIKFVDRV QKSCQNGKLD LSEQSLGPNS AKIVSEIIKN NSNFSTLNLN RNNIKDEGAL
     LIAQAILNNP NICIIDVSNN NLSSQGCQFF FELLMSTESI YSLNISSPDS YNRNKMNFET
     SKSICQMLKV NQTLSFLDLS HSLLGPNGLN KIVKGLKENK SLVYLNLSFN ELGPECGKIL
     QPILLNSKIV ELNLSNNKIG NQSLDKIGET ILTGQGTFAI EILNFSYNQI NSDGLCDFMK
     AIMRNSKIQK LYFDGNSFQD PVNDSLTNYF IANSSLKTFS LRDCSFHANL IENVSLGLQQ
     NDSLKVLDIS HNYIGDEGLT YLAECLSKEN KSLEELYMKR CNIQEKGGVE LAKIVACHPK
     LSKIDVSHNL MSEESGTYIA TNIRTNWNIV LFDIEKNYIR YDQHVEIKKL VKRNQEFSKM
     KEPVCLLNTL SNLRSSEIKK EDLEQRKNNL IQKERINNND TSQLAVQIQK AEQVLVQTEE
     VVKQQQLEMR AEMDQIMKEL KNLDIIQNTQ VNDLLKEIDK QFEKNQNTRK EIDTMRKEIK
     TKTQDMIHRK NLLLQQLAIQ KKIVKEEELK AKSEEMAYQM FSQNVENLKK KIELLKQGKL
     PPSDQQLQNQ KTLSTPNSPQ TKQGNFSFPP GAENTNTKTS AFKKPKTKTS NSATNIKNKK
     QQNKNDTKK
//