ID Q24GH2_TETTS Unreviewed; 221 AA.
AC Q24GH2;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Mpv17/PMP22 family protein {ECO:0000313|EMBL:EAS06899.1};
GN ORFNames=TTHERM_00726180 {ECO:0000313|EMBL:EAS06899.1};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS06899.1, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC {ECO:0000256|ARBA:ARBA00006824, ECO:0000256|RuleBase:RU363053}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU363053}.
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DR EMBL; GG662257; EAS06899.1; -; Genomic_DNA.
DR RefSeq; XP_001027141.1; XM_001027141.1.
DR AlphaFoldDB; Q24GH2; -.
DR STRING; 312017.Q24GH2; -.
DR EnsemblProtists; EAS06899; EAS06899; TTHERM_00726180.
DR GeneID; 7845517; -.
DR KEGG; tet:TTHERM_00726180; -.
DR eggNOG; KOG1944; Eukaryota.
DR HOGENOM; CLU_049109_8_0_1; -.
DR InParanoid; Q24GH2; -.
DR OMA; NLYFIPV; -.
DR OrthoDB; 314578at2759; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007248; Mpv17_PMP22.
DR PANTHER; PTHR11266; PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17; 1.
DR Pfam; PF04117; Mpv17_PMP22; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363053};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Transmembrane {ECO:0000256|RuleBase:RU363053};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363053}.
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
SQ SEQUENCE 221 AA; 25417 MW; 96558F637D489B7C CRC64;
MKMIRSVLRL VERYNKYTEQ NPAKSIILST GFLFGAGDLL TQQIDRYYER KEHEGDSNYQ
VTPINKMRIA HMCLYGLTFM GPFSYVWYTH ALPKIAPITI EACKSQLFKK IAIDQVVGSG
IQYSSFLVAM TLLGGKSISE NSKKIKEDFV QCCISDVFVW PWVQFLNFRY VPIHMQALYV
NFVSVFWNAY ISAIHHTPVV VEKPSLQKES NNLFKGAMLA F
//
