ID Q24I93_TETTS Unreviewed; 339 AA.
AC Q24I93;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2007, sequence version 2.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Peptidase C13 family protein {ECO:0000313|EMBL:EAS07504.2};
GN ORFNames=TTHERM_01035670 {ECO:0000313|EMBL:EAS07504.2};
OS Tetrahymena thermophila (strain SB210).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC Tetrahymena.
OX NCBI_TaxID=312017 {ECO:0000313|EMBL:EAS07504.2, ECO:0000313|Proteomes:UP000009168};
RN [1] {ECO:0000313|Proteomes:UP000009168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB210 {ECO:0000313|Proteomes:UP000009168};
RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286;
RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R.,
RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L.,
RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M.,
RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., Sun L.,
RA Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., Wang Y.,
RA Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., Weinberg Z.,
RA Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., Gorovsky M.A.,
RA Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., Stover N.A.,
RA Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., Barbeau R.A.,
RA Hamilton E.P., Orias E.;
RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a
RT model eukaryote.";
RL PLoS Biol. 4:1620-1642(2006).
CC -!- PATHWAY: Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004687}.
CC -!- SIMILARITY: Belongs to the peptidase C13 family.
CC {ECO:0000256|ARBA:ARBA00009941}.
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DR EMBL; GG662225; EAS07504.2; -; Genomic_DNA.
DR RefSeq; XP_001027746.2; XM_001027746.3.
DR AlphaFoldDB; Q24I93; -.
DR STRING; 312017.Q24I93; -.
DR MEROPS; C13.005; -.
DR EnsemblProtists; EAS07504; EAS07504; TTHERM_01035670.
DR GeneID; 7837643; -.
DR KEGG; tet:TTHERM_01035670; -.
DR eggNOG; KOG1349; Eukaryota.
DR HOGENOM; CLU_1002735_0_0_1; -.
DR InParanoid; Q24I93; -.
DR OMA; YIKMQDT; -.
DR OrthoDB; 1122658at2759; -.
DR UniPathway; UPA00196; -.
DR Proteomes; UP000009168; Unassembled WGS sequence.
DR GO; GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
DR GO; GO:0003923; F:GPI-anchor transamidase activity; IEA:InterPro.
DR GO; GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR028361; GPI_transamidase.
DR InterPro; IPR001096; Peptidase_C13.
DR PANTHER; PTHR48067; GPI-ANCHOR TRANSAMIDASE; 1.
DR PANTHER; PTHR48067:SF1; GPI-ANCHOR TRANSAMIDASE; 1.
DR Pfam; PF01650; Peptidase_C13; 1.
DR PRINTS; PR00776; HEMOGLOBNASE.
PE 3: Inferred from homology;
KW GPI-anchor biosynthesis {ECO:0000256|ARBA:ARBA00022502};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000009168};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..339
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004202285"
SQ SEQUENCE 339 AA; 39291 MW; C09989EA93D28DD3 CRC64;
MKKLQSSLSL VIVFLLLICQ VSSEKAHDLK VIIMSTSKFW FNFRQATNTL LIYDVLKKNG
VKDEDIILMI PENSACNPRN NNPGVVCHLE LESEPNLYRN SEIDYKLSDV NVHTLTNMLR
GKYHRYTPRS KRLVTNKNTK ILTYFTGHGG SGYIKMQDTD VMMDEEMRVA LEEFNIKNFY
NEMLMFSDSC SAATIFEKLK PDTNPNIFGI GSSSRGQYSY SYGKDSHINL SIVDRFSRAN
YLFLTNEFVR NKDSLLSDIM REWTKEYLQG DFSYTNTHAR KDSKNIYLKD FFTNLNPTTS
NIMEMSPKKD HHYDQLEALF GEIMSQPSTD FSIENKPFI
//
