ID Q24WN1_DESHY Unreviewed; 440 AA.
AC Q24WN1;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN OrderedLocusNames=DSY1772 {ECO:0000313|EMBL:BAE83561.1};
OS Desulfitobacterium hafniense (strain Y51).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfitobacterium.
OX NCBI_TaxID=138119 {ECO:0000313|EMBL:BAE83561.1, ECO:0000313|Proteomes:UP000001946};
RN [1] {ECO:0000313|EMBL:BAE83561.1, ECO:0000313|Proteomes:UP000001946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y51 {ECO:0000313|EMBL:BAE83561.1,
RC ECO:0000313|Proteomes:UP000001946};
RX PubMed=16513756; DOI=10.1128/JB.188.6.2262-2274.2006;
RA Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K.,
RA Inatomi K., Furukawa K., Inui M., Yukawa H.;
RT "Complete genome sequence of the dehalorespiring bacterium
RT Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides
RT ethenogenes 195.";
RL J. Bacteriol. 188:2262-2274(2006).
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DR EMBL; AP008230; BAE83561.1; -; Genomic_DNA.
DR RefSeq; WP_011459874.1; NC_007907.1.
DR AlphaFoldDB; Q24WN1; -.
DR STRING; 138119.DSY1772; -.
DR KEGG; dsy:DSY1772; -.
DR eggNOG; COG2108; Bacteria.
DR HOGENOM; CLU_620840_0_0_9; -.
DR Proteomes; UP000001946; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43288; BIOTIN SYNTHASE-RELATED PROTEIN, RADICAL SAM SUPERFAMILY; 1.
DR PANTHER; PTHR43288:SF1; GLYCYL-RADICAL ENZYME ACTIVATING ENZYME MJ0021-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001946};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 85..291
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 440 AA; 51314 MW; 4C0A37C990F6D540 CRC64;
MIIETTKQNL SQIRNPEFSQ YAQIYARVYD HFIDQIKQTG MALDENLEKE TAAKLEKIKQ
MQGVFRNSDK SIVNTWISSA CEACQKGVGT VTMYVSLMCH RNCYFCFNPN QEDYEHFTHN
KRDLVSELTQ HLKHGPKLTH LALTGGEPLL HKKEMLDFFR LAKEKSPKTH TRLYTSGDFL
DREILQDLKD AGLSEIRFSI KMEDPERLKQ EVYERIALSK EFIPDVMVEM PVLPGSFAEM
KEVLLELDRI GISGINLLEF CFPFNNADEF IKRGYKVKNP PFKVLYDYWY AGGLPISRSE
LECLDLMAFA LEEKLQLGVH YCSLENKQTG QIYQQNYGQK VSSLMFFSPR DYFFKSAKVF
GEDISKVKKV FKKKNVTQYQ FNADYNYLEF HVSQIKLLKD LDIEVGISSN VMEVREDGKY
LRELKIDRTY PKDFDLSKDI
//
