ID Q24XH4_DESHY Unreviewed; 246 AA.
AC Q24XH4;
DT 18-APR-2006, integrated into UniProtKB/TrEMBL.
DT 18-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE RecName: Full=Cobalt transport protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
DE Short=ECF transporter S component CbiM {ECO:0000256|HAMAP-Rule:MF_01462};
GN Name=cbiM {ECO:0000256|HAMAP-Rule:MF_01462,
GN ECO:0000313|EMBL:BAE83268.1};
GN OrderedLocusNames=DSY1479 {ECO:0000313|EMBL:BAE83268.1};
OS Desulfitobacterium hafniense (strain Y51).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfitobacterium.
OX NCBI_TaxID=138119 {ECO:0000313|EMBL:BAE83268.1, ECO:0000313|Proteomes:UP000001946};
RN [1] {ECO:0000313|EMBL:BAE83268.1, ECO:0000313|Proteomes:UP000001946}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y51 {ECO:0000313|EMBL:BAE83268.1,
RC ECO:0000313|Proteomes:UP000001946};
RX PubMed=16513756; DOI=10.1128/JB.188.6.2262-2274.2006;
RA Nonaka H., Keresztes G., Shinoda Y., Ikenaga Y., Abe M., Naito K.,
RA Inatomi K., Furukawa K., Inui M., Yukawa H.;
RT "Complete genome sequence of the dehalorespiring bacterium
RT Desulfitobacterium hafniense Y51 and comparison with Dehalococcoides
RT ethenogenes 195.";
RL J. Bacteriol. 188:2262-2274(2006).
CC -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC CbiMNOQ involved in cobalt import. {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC (S components, CbiM and CbiN) of unknown stoichimetry.
CC {ECO:0000256|HAMAP-Rule:MF_01462}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_01462};
CC Multi-pass membrane protein {ECO:0000256|HAMAP-Rule:MF_01462}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CbiM family. {ECO:0000256|HAMAP-
CC Rule:MF_01462}.
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DR EMBL; AP008230; BAE83268.1; -; Genomic_DNA.
DR RefSeq; WP_005812271.1; NC_007907.1.
DR AlphaFoldDB; Q24XH4; -.
DR STRING; 138119.DSY1479; -.
DR KEGG; dsy:DSY1479; -.
DR eggNOG; COG0310; Bacteria.
DR HOGENOM; CLU_052508_3_0_9; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000001946; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.1760.20; -; 1.
DR HAMAP; MF_01462; CbiM; 1.
DR InterPro; IPR018024; CbiM.
DR InterPro; IPR002751; CbiM/NikMN.
DR NCBIfam; TIGR00123; cbiM; 1.
DR PANTHER; PTHR43627; -; 1.
DR PANTHER; PTHR43627:SF1; COBALT TRANSPORT PROTEIN CBIM; 1.
DR Pfam; PF01891; CbiM; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Cobalt {ECO:0000256|ARBA:ARBA00023285, ECO:0000256|HAMAP-Rule:MF_01462};
KW Cobalt transport {ECO:0000256|ARBA:ARBA00022426, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01462};
KW Reference proteome {ECO:0000313|Proteomes:UP000001946};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_01462};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01462}.
FT TRANSMEM 34..55
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 67..85
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 97..125
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 132..154
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 174..199
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
FT TRANSMEM 211..232
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01462"
SQ SEQUENCE 246 AA; 26047 MW; 03C682E085467ED5 CRC64;
MNKRIQLFIG LVLMMFFIPY KASAMHIMEG FLQPGWAIAW GALAIPFVVL GIFSIKKTIS
LNPRLKILLA MAGAFVFVLS ALKLPSVTGS CSHPTGVGFG AILFGPTAMA VIGVIVLLFQ
ALLLAHGGLT TLGANTFSMA VVGPFVAFGV YKLVQKFKGP QWLGVFLAAS LGDLATYVMT
SIQLALAFPS EVGGFAASLT KFASIFAVTQ IPLAISEGIL TVIIFNALAS YGKSELQDLK
LLTKEV
//
