ID Q26623_STRPU Unreviewed; 402 AA.
AC Q26623;
DT 01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT 01-NOV-1996, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=Tektin {ECO:0000256|RuleBase:RU367040};
OS Strongylocentrotus purpuratus (Purple sea urchin).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC Strongylocentrotus.
OX NCBI_TaxID=7668 {ECO:0000313|EMBL:AAB02680.1};
RN [1] {ECO:0000313|EMBL:AAB02680.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=8609631; DOI=10.1006/jmbi.1996.0170;
RA Norrander J.M., Perrone C.A., Amos L.A., Linck R.W.;
RT "Structural comparison of tektins and evidence for their determination of
RT complex spacings in flagellar microtubules.";
RL J. Mol. Biol. 257:385-397(1996).
RN [2] {ECO:0000313|Proteomes:UP000007110}
RP NUCLEOTIDE SEQUENCE.
RA Murali S., Liu Y., Vee V., English A., Wang M., Skinner E., Han Y.,
RA Muzny D.M., Worley K.C., Gibbs R.A.;
RT "Genome sequencing for Strongylocentrotus purpuratus.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:XP_782318}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JAN-2021) to UniProtKB.
RN [4] {ECO:0007829|PDB:8SNB}
RP STRUCTURE BY ELECTRON MICROSCOPY (3.30 ANGSTROMS).
RX PubMed=37327785; DOI=10.1016/j.cell.2023.05.026;
RA Leung M.R., Zeng J., Wang X., Roelofs M.C., Huang W., Zenezini Chiozzi R.,
RA Hevler J.F., Heck A.J.R., Dutcher S.K., Brown A., Zhang R.,
RA Zeev-Ben-Mordehai T.;
RT "Structural specializations of the sperm tail.";
RL Cell 186:2880-2896.e17(2023).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000256|RuleBase:RU367040}. Cytoplasm, cytoskeleton, flagellum
CC axoneme {ECO:0000256|ARBA:ARBA00004611}.
CC -!- SIMILARITY: Belongs to the tektin family.
CC {ECO:0000256|ARBA:ARBA00007209, ECO:0000256|RuleBase:RU367040}.
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DR EMBL; U38523; AAB02680.1; -; mRNA.
DR PIR; S71137; S71137.
DR RefSeq; NP_999788.1; NM_214623.1.
DR RefSeq; XP_011668381.1; XM_011670079.1.
DR RefSeq; XP_782318.1; XM_777225.4.
DR PDB; 8SNB; EM; 3.30 A; 8Q/8R/8S/8T/8U=1-402.
DR SMR; Q26623; -.
DR STRING; 7668.Q26623; -.
DR EnsemblMetazoa; XM_777225; XP_782318; LOC576964.
DR GeneID; 373481; -.
DR GeneID; 576964; -.
DR KEGG; spu:576964; -.
DR CTD; 83659; -.
DR eggNOG; KOG2685; Eukaryota.
DR HOGENOM; CLU_033588_2_2_1; -.
DR OMA; VELCYDT; -.
DR OrthoDB; 2875854at2759; -.
DR Proteomes; UP000007110; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR GO; GO:0060294; P:cilium movement involved in cell motility; IBA:GO_Central.
DR InterPro; IPR048256; Tektin-like.
DR InterPro; IPR000435; Tektins.
DR PANTHER; PTHR19960; TEKTIN; 1.
DR PANTHER; PTHR19960:SF25; TEKTIN-1; 1.
DR Pfam; PF03148; Tektin; 1.
DR PRINTS; PR00511; TEKTIN.
PE 1: Evidence at protein level;
KW 3D-structure {ECO:0007829|PDB:8SNB};
KW Cell projection {ECO:0000256|RuleBase:RU367040};
KW Cilium {ECO:0000256|RuleBase:RU367040};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Flagellum {ECO:0000256|RuleBase:RU367040};
KW Reference proteome {ECO:0000313|Proteomes:UP000007110}.
FT COILED 24..94
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 275..302
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 341..375
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 402 AA; 46620 MW; B2480A5BD1241E2C CRC64;
MSKLIKAPQR FTHGEWNYSN HANYNSAEKQ RASAERLIDE SDRLIDETDE ATKKTQRDVN
KKFEQRLDDV TYWKDELDRK LKDSKDEIEM LLAYKTRLEN ALEACREPLA IVNQCLNDRE
GRIGIDLVHD DVEKNLLKER EVIMGVMALL QKTLDQVIEQ IRIMRSRRYN LEKDLTDKFG
ALDIDQDCRN LRDDNSTLQF KGGVAKIETN SVTPEDWQSF SNENILKAER DRKNSADLRA
VVDSLLKTTA DDMQQQVDDT NLAFSKRIRE TDMTKGKLET HLAKVEGQMR EMEENIQKLQ
KGVDDKMGPK KLSETRLDAR TNRPNVELCR DPVQYRLIGE VTEINTSIAR LQATLAQAQS
ELKGLIRNQL NLQEDIDIKS QSLNVDDTQC MTLRRSINIK RY
//
