ID Q28D26_XENTR Unreviewed; 321 AA.
AC Q28D26; F6SKS3;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 125.
DE SubName: Full=Reticulocalbin 1, EF-hand calcium binding domain {ECO:0000313|EMBL:CAJ81551.1};
DE SubName: Full=Reticulocalbin-1 precursor {ECO:0000313|RefSeq:NP_001016768.1};
GN Name=rcn1 {ECO:0000313|EMBL:CAJ81551.1,
GN ECO:0000313|RefSeq:NP_001016768.1,
GN ECO:0000313|Xenbase:XB-GENE-490301};
GN Synonyms=pig20 {ECO:0000313|RefSeq:NP_001016768.1}, rcal
GN {ECO:0000313|RefSeq:NP_001016768.1}, rcn
GN {ECO:0000313|RefSeq:NP_001016768.1};
GN ORFNames=TGas057n07.1-001 {ECO:0000313|EMBL:CAJ81551.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:CAJ81551.1};
RN [1] {ECO:0000313|RefSeq:NP_001016768.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:CAJ81551.1}
RP NUCLEOTIDE SEQUENCE.
RA Amaya E., Ashurst J.L., Bonfield J.K., Croning M.D.R., Chen C-K.,
RA Davies R.M., Francis M.D., Garrett N., Gilchrist M.J., Grafham D.V.,
RA McLaren S.R., Papalopulu N., Rogers J., Smith J.C., Taylor R.G., Voigt J.,
RA Zorn A.M.;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:NP_001016768.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CREC family.
CC {ECO:0000256|ARBA:ARBA00006431}.
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DR EMBL; CR855743; CAJ81551.1; -; mRNA.
DR RefSeq; NP_001016768.1; NM_001016768.2.
DR RefSeq; XP_012816577.1; XM_012961123.2.
DR RefSeq; XP_012816578.1; XM_012961124.1.
DR RefSeq; XP_012816579.1; XM_012961125.2.
DR STRING; 8364.ENSXETP00000028887; -.
DR PaxDb; 8364-ENSXETP00000058951; -.
DR GeneID; 549522; -.
DR KEGG; xtr:549522; -.
DR AGR; Xenbase:XB-GENE-490301; -.
DR CTD; 5954; -.
DR Xenbase; XB-GENE-490301; rcn1.
DR HOGENOM; CLU_044718_0_1_1; -.
DR OrthoDB; 4490703at2759; -.
DR PhylomeDB; Q28D26; -.
DR Proteomes; UP000008143; Chromosome 4.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd16229; EFh_CREC_RCN1; 1.
DR Gene3D; 1.10.238.10; EF-hand; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR027241; Rcn1.
DR PANTHER; PTHR10827; RETICULOCALBIN; 1.
DR PANTHER; PTHR10827:SF17; RETICULOCALBIN-1; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00054; EFh; 4.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 5.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 2: Evidence at transcript level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001016768.1}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..321
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001016768.1"
FT /id="PRO_5033206209"
FT DOMAIN 69..104
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 105..140
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 193..228
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 321 AA; 37963 MW; C68F1B49258328A6 CRC64;
MDPHSVLCLL LVLCTGEVLC KPTFRKERIR LDPELNNQIP EENQSFQQDH EAFLGKDDAK
TFDQLTPEES KDRLGKIINR IDSDSDGLIT TEELTAWIKR VQKRYVYENV ARVWKDYDVN
KDNTISWEEY KQATYGYYLA NPEEFQDAAE QFSFKKMLPR DERRFKQADL NGDLEANREE
FTSFLHPEEF EHMKDIVILE TLEDIDKNGD GFVDQDEYIA DMFSHEEGQP EPDWVATERE
QFADFRDINK DGKMDKEEIR HWILPQDYDH AQAEARHLIY ESDLDKDKVL TKEEVLQNWN
MFVGSQATNY GEDLTRNHDE L
//
