ID Q28KL0_JANSC Unreviewed; 719 AA.
AC Q28KL0;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=alpha-galactosidase {ECO:0000256|ARBA:ARBA00012755};
DE EC=3.2.1.22 {ECO:0000256|ARBA:ARBA00012755};
GN OrderedLocusNames=Jann_3835 {ECO:0000313|EMBL:ABD56752.1};
OS Jannaschia sp. (strain CCS1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=290400 {ECO:0000313|EMBL:ABD56752.1, ECO:0000313|Proteomes:UP000008326};
RN [1] {ECO:0000313|Proteomes:UP000008326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCS1 {ECO:0000313|Proteomes:UP000008326};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J.,
RA Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W.,
RA Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABD56752.1, ECO:0000313|Proteomes:UP000008326}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCS1 {ECO:0000313|EMBL:ABD56752.1,
RC ECO:0000313|Proteomes:UP000008326};
RX PubMed=17526795; DOI=10.1128/AEM.02580-06;
RA Moran M.A., Belas R., Schell M.A., Gonzalez J.M., Sun F., Sun S.,
RA Binder B.J., Edmonds J., Ye W., Orcutt B., Howard E.C., Meile C.,
RA Palefsky W., Goesmann A., Ren Q., Paulsen I., Ulrich L.E., Thompson L.S.,
RA Saunders E., Buchan A.;
RT "Ecological genomics of marine Roseobacters.";
RL Appl. Environ. Microbiol. 73:4559-4569(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing alpha-D-galactose
CC residues in alpha-D-galactosides, including galactose
CC oligosaccharides, galactomannans and galactolipids.; EC=3.2.1.22;
CC Evidence={ECO:0000256|ARBA:ARBA00001255};
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DR EMBL; CP000264; ABD56752.1; -; Genomic_DNA.
DR AlphaFoldDB; Q28KL0; -.
DR STRING; 290400.Jann_3835; -.
DR CAZy; GH36; Glycoside Hydrolase Family 36.
DR KEGG; jan:Jann_3835; -.
DR eggNOG; COG3345; Bacteria.
DR HOGENOM; CLU_009640_3_1_5; -.
DR OrthoDB; 9758822at2; -.
DR Proteomes; UP000008326; Chromosome.
DR GO; GO:0004557; F:alpha-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd14791; GH36; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 2.70.98.60; alpha-galactosidase from lactobacil brevis; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR038417; Alpga-gal_N_sf.
DR InterPro; IPR002252; Glyco_hydro_36.
DR InterPro; IPR031705; Glyco_hydro_36_C.
DR InterPro; IPR031704; Glyco_hydro_36_N.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR43053:SF3; ALPHA-GALACTOSIDASE C-RELATED; 1.
DR PANTHER; PTHR43053; GLYCOSIDASE FAMILY 31; 1.
DR Pfam; PF16874; Glyco_hydro_36C; 1.
DR Pfam; PF16875; Glyco_hydro_36N; 1.
DR Pfam; PF02065; Melibiase; 1.
DR PRINTS; PR00743; GLHYDRLASE36.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ABD56752.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008326}.
FT DOMAIN 48..267
FT /note="Glycosyl hydrolase family 36 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16875"
FT DOMAIN 628..706
FT /note="Glycosyl hydrolase family 36 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16874"
SQ SEQUENCE 719 AA; 80702 MW; F2832FC8FE81A8E7 CRC64;
MDIVVDDKIA DGLPVGTKAD VAKRDVRTWR LDDDGRQTLV LAATGDRLPQ VVYWGAPLPM
TDDLTTLQAA HALDVTGGML DENPDLSLCP EAIRTFPGQP GLILRDGDGT PLLPKFCYEN
EELSEDGLVL IYADEPNGLT LSFHFATDPS TRIITAKTRL DATRPVHLHW LAAPVLPAPQ
QSEEMIDFAG RWTGEFQTNR TAWSPGMRYR ENRTGRTGHE HFPGLLIPVT GCTNTQGEAY
GFHYGWSGGH KMIAEELPDG RRQIQFGHAA RMETQAATTF SSATLYVTYS GVGLNGCAVS
FQRHLRDRIV TWPDPDRPRP VHYNCWEAVY FDHKLPVLKD IAERAADLGA ERFVLDDGWF
GQRDDDTRSL SDWEVDVRKY PDGLGPLIDH VHGLGMTFGI WFEPEMINPD SDIHRAHPDW
ALGGEDQTLG RQQKALNMAL PEVRDFIYGR MAAVLAAHPI DYIKWDHNRV LPMPDADQTR
GSYALIDRLR ADFPHVEIES CASGGGRIDF GIMQRTQRIW LSDSNDALER LRIQHDAALF
LPIAVTGSHV GPRRCHTSGR VFDISFRAWV AAQRHMGFEM DPRELDAREA AVLREVTSWW
KFNRDWMLTA DILRLDSADP AVIAEQQMTR DGDRFVVFAG KAATSDQIAP RPLRLTALDD
QARYRITLMN RGTAPALSRG MPALKDGPIE VSGAWLMHHG LTLPWNYPDT MWVLEGERL
//
