ID Q29F33_DROPS Unreviewed; 355 AA.
AC Q29F33; A0A6I8UEH6;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=G protein alpha i subunit isoform X1 {ECO:0000313|RefSeq:XP_001354187.1};
GN Name=LOC4814006 {ECO:0000313|RefSeq:XP_001354187.1};
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245 {ECO:0000313|Proteomes:UP000001819, ECO:0000313|RefSeq:XP_001354187.1};
RN [1] {ECO:0000313|RefSeq:XP_001354187.1}
RP IDENTIFICATION.
RC STRAIN=MV2-25 {ECO:0000313|RefSeq:XP_001354187.1};
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_001354187.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_001354187.1; XM_001354151.4.
DR AlphaFoldDB; Q29F33; -.
DR SMR; Q29F33; -.
DR STRING; 46245.Q29F33; -.
DR EnsemblMetazoa; FBtr0289817; FBpp0288255; FBgn0070098.
DR GeneID; 4814006; -.
DR KEGG; dpo:4814006; -.
DR eggNOG; KOG0082; Eukaryota.
DR HOGENOM; CLU_014184_6_0_1; -.
DR InParanoid; Q29F33; -.
DR OMA; GMGCTVS; -.
DR Proteomes; UP000001819; Chromosome X.
DR Bgee; FBgn0070098; Expressed in female reproductive system and 2 other cell types or tissues.
DR ExpressionAtlas; Q29F33; baseline.
DR GO; GO:0045179; C:apical cortex; IEA:EnsemblMetazoa.
DR GO; GO:0003677; F:DNA binding; IEA:EnsemblMetazoa.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0055059; P:asymmetric neuroblast division; IEA:EnsemblMetazoa.
DR GO; GO:0045167; P:asymmetric protein localization involved in cell fate determination; IEA:EnsemblMetazoa.
DR GO; GO:0032291; P:axon ensheathment in central nervous system; IEA:EnsemblMetazoa.
DR GO; GO:0019722; P:calcium-mediated signaling; IEA:EnsemblMetazoa.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:EnsemblMetazoa.
DR GO; GO:0060857; P:establishment of glial blood-brain barrier; IEA:EnsemblMetazoa.
DR GO; GO:0051294; P:establishment of spindle orientation; IEA:EnsemblMetazoa.
DR GO; GO:0032880; P:regulation of protein localization; IEA:EnsemblMetazoa.
DR GO; GO:0019991; P:septate junction assembly; IEA:EnsemblMetazoa.
DR GO; GO:0007419; P:ventral cord development; IEA:EnsemblMetazoa.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001408; Gprotein_alpha_I.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218:SF227; G PROTEIN ALPHA I SUBUNIT; 1.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00441; GPROTEINAI.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001819};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
SQ SEQUENCE 355 AA; 40601 MW; C72FFC6E0E04EE00 CRC64;
MGCAVSTARD KEAIERSKNI DRALRAEGER AASEVKLLLL GAGESGKSTI VKQMKIIHET
GYSQEECEEY RRVVYSNTVQ SLMVIIRAMG RLKIEFADQG KTDIARQFFT HASAADEGIL
LPEIVLLMKK LWSDGGVQQS FARSREYQLN DSAGYYLNSL DRIAQPNYIP TQQDVLRTRV
KTTGIIETHF SCKQLHFKLF DVGGQRSERK KWIHCFEGVT AIIFCVALSG YDLVLAEDEE
MNRMIESLKL FDSICNSKWF VETSIILFLN KKDLFEEKIK RSPLTICFPE YSGTNTFEEA
ANYIRMKFEN LNKRKDQKEI YTHLTCATDT NNVKFVFDAV TDVIIKNNLK QIGLF
//
