ID Q29F60_DROPS Unreviewed; 392 AA.
AC Q29F60; A0A6I8UEF8;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 04-APR-2006, sequence version 1.
DT 27-MAR-2024, entry version 118.
DE SubName: Full=T-box transcription factor TBX6 {ECO:0000313|RefSeq:XP_001354158.1};
GN Name=LOC4814004 {ECO:0000313|RefSeq:XP_001354158.1};
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245 {ECO:0000313|Proteomes:UP000001819, ECO:0000313|RefSeq:XP_001354158.1};
RN [1] {ECO:0000313|RefSeq:XP_001354158.1}
RP IDENTIFICATION.
RC STRAIN=MV2-25 {ECO:0000313|RefSeq:XP_001354158.1};
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_001354158.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_001354158.1; XM_001354122.4.
DR AlphaFoldDB; Q29F60; -.
DR SMR; Q29F60; -.
DR STRING; 46245.Q29F60; -.
DR EnsemblMetazoa; FBtr0289886; FBpp0288324; FBgn0078682.
DR GeneID; 4814004; -.
DR KEGG; dpo:4814004; -.
DR eggNOG; KOG3585; Eukaryota.
DR HOGENOM; CLU_024824_2_1_1; -.
DR InParanoid; Q29F60; -.
DR OMA; ELMDMRM; -.
DR Proteomes; UP000001819; Chromosome X.
DR ExpressionAtlas; Q29F60; baseline.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:EnsemblMetazoa.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0061327; P:anterior Malpighian tubule development; IEA:EnsemblMetazoa.
DR GO; GO:0035051; P:cardiocyte differentiation; IEA:EnsemblMetazoa.
DR GO; GO:0035294; P:determination of wing disc primordium; IEA:EnsemblMetazoa.
DR GO; GO:0001700; P:embryonic development via the syncytial blastoderm; IEA:EnsemblMetazoa.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:EnsemblMetazoa.
DR CDD; cd20681; T-box_Drosocross-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR002070; TF_Brachyury.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF51; DORSOCROSS1, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00938; BRACHYURY.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000001819};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
SQ SEQUENCE 392 AA; 43539 MW; 60A64E4FB6A263D4 CRC64;
MLSMQELIEV RMQQQLAHEI YRQQIMQRIP DPFPAMLPFN MPQPQIMLPN RPSLPGVEAK
LENNDLWQQF HKIGTEMIIT KSGRRMFPSM RVSLSGLEEE ASYCVLLEMV PIGDCRYKFS
GSQWVPAGGA EPQSPQRMYL HPDSPATGAH WQSQALLFNK VKLTNNTLDS SGHIVLASMH
KYQPRLHIIR SSELTQLPWA PQQAFIFPET EFVAVTAYQN DRITKLKIDN NPFAKGFRES
GQSRCKRKLN STSHSSPESE DDGSSVSSCE SPQSKRQRLD CEQDSQGSLS PVPYYPSSTV
AEVAASLSPS LSPYHRHPLS YAAPNFAAAY FCGVPQVPPM PLPSALCQVP TPVPVSALQL
STSPASSSIT NTPRTTTSTK RNSFSISAIL AY
//
