ID Q29M53_DROPS Unreviewed; 237 AA.
AC Q29M53; A0A6I8UK16;
DT 04-APR-2006, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2008, sequence version 2.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|RefSeq:XP_001356776.2};
GN Name=LOC4817269 {ECO:0000313|RefSeq:XP_001356776.2};
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245 {ECO:0000313|Proteomes:UP000001819, ECO:0000313|RefSeq:XP_001356776.2};
RN [1] {ECO:0000313|RefSeq:XP_001356776.2}
RP IDENTIFICATION.
RC STRAIN=MV2-25 {ECO:0000313|RefSeq:XP_001356776.2};
RC TISSUE=Whole body {ECO:0000313|RefSeq:XP_001356776.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the alkB family.
CC {ECO:0000256|ARBA:ARBA00007879}.
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DR RefSeq; XP_001356776.2; XM_001356740.4.
DR AlphaFoldDB; Q29M53; -.
DR SMR; Q29M53; -.
DR STRING; 46245.Q29M53; -.
DR EnsemblMetazoa; FBtr0281456; FBpp0279894; FBgn0079385.
DR GeneID; 4817269; -.
DR KEGG; dpo:4817269; -.
DR eggNOG; KOG3200; Eukaryota.
DR HOGENOM; CLU_059836_1_1_1; -.
DR InParanoid; Q29M53; -.
DR OMA; ILQDEMY; -.
DR Proteomes; UP000001819; Chromosome 4.
DR Bgee; FBgn0079385; Expressed in female reproductive system and 2 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.590; Alpha-ketoglutarate-dependent dioxygenase AlkB-like; 1.
DR InterPro; IPR027450; AlkB-like.
DR InterPro; IPR037151; AlkB-like_sf.
DR InterPro; IPR032862; ALKBH6.
DR InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR PANTHER; PTHR46030; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6; 1.
DR PANTHER; PTHR46030:SF1; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6; 1.
DR Pfam; PF13532; 2OG-FeII_Oxy_2; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51471; FE2OG_OXY; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964,
KW ECO:0000313|RefSeq:XP_001356776.2}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001819}.
SQ SEQUENCE 237 AA; 26741 MW; B72D2BD4195B2495 CRC64;
MDFTGFEVRK CPPTAMYIPN FITSEEEQRI LSHIERTPKP RWTQLLNRRL VNYGGVPHPN
GMIAEEIPEW LQSYVDKVNN LGVFESQNAN HVLVNEYLPG QGILPHTDGP LFYPIISTIS
CGAHTVLEFA KREGTTAEEG DASVGDGDGD SGQAGRVVLF KLLLEPRSLL ILKDTLYSDY
LHSIAETKED VLCDRICNYD LCETTYKMGD HLVRRAPRIS LTIRNVPKTS KMKLKFC
//
