ID Q2F5R2_BOMMO Unreviewed; 480 AA.
AC Q2F5R2;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=G protein pathway suppressor 1 {ECO:0000313|EMBL:ABD36305.1};
GN Name=693104 {ECO:0000313|EnsemblMetazoa:NP_001040322.1};
OS Bombyx mori (Silk moth).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC Bombycidae; Bombycinae; Bombyx.
OX NCBI_TaxID=7091 {ECO:0000313|EMBL:ABD36305.1};
RN [1] {ECO:0000313|EMBL:ABD36305.1}
RP NUCLEOTIDE SEQUENCE.
RA Niu B.L., Meng Z.Q., Weng H.B., Shen W.F., He L.H., Zheng K.F., Ye S.T.,
RA Lin T.B., Chen J.E.;
RT "Blast silkworm EST database for functional genes.";
RL Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=p50T {ECO:0000313|Proteomes:UP000005204};
RX PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004;
RG International Silkworm Genome Consortium;
RT "The genome of a lepidopteran model insect, the silkworm Bombyx mori.";
RL Insect Biochem. Mol. Biol. 38:1036-1045(2008).
RN [3] {ECO:0000313|EnsemblMetazoa:NP_001040322.1}
RP IDENTIFICATION.
RC STRAIN=p50T (Dazao) {ECO:0000313|EnsemblMetazoa:NP_001040322.1};
RG EnsemblMetazoa;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CSN1 family.
CC {ECO:0000256|ARBA:ARBA00008793}.
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DR EMBL; DQ311361; ABD36305.1; -; mRNA.
DR RefSeq; NP_001040322.1; NM_001046857.1.
DR AlphaFoldDB; Q2F5R2; -.
DR SMR; Q2F5R2; -.
DR STRING; 7091.Q2F5R2; -.
DR PaxDb; 7091-BGIBMGA011770-TA; -.
DR EnsemblMetazoa; NM_001046857.1; NP_001040322.1; LOC693104.
DR GeneID; 693104; -.
DR KEGG; bmor:693104; -.
DR eggNOG; KOG0686; Eukaryota.
DR HOGENOM; CLU_022348_1_0_1; -.
DR InParanoid; Q2F5R2; -.
DR OMA; IYLQNWA; -.
DR OrthoDB; 1601at2759; -.
DR Proteomes; UP000005204; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.570; -; 1.
DR InterPro; IPR048624; CSN1_C.
DR InterPro; IPR000717; PCI_dom.
DR InterPro; IPR019585; Rpn7/CSN1.
DR InterPro; IPR045135; Rpn7_N.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR14145; 26S PROTESOME SUBUNIT 6; 1.
DR PANTHER; PTHR14145:SF2; COP9 SIGNALOSOME COMPLEX SUBUNIT 1; 1.
DR Pfam; PF21151; CSN1_C; 1.
DR Pfam; PF01399; PCI; 1.
DR Pfam; PF10602; RPN7; 1.
DR SMART; SM00088; PINT; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50250; PCI; 1.
PE 2: Evidence at transcript level;
KW Reference proteome {ECO:0000313|Proteomes:UP000005204}.
FT DOMAIN 252..414
FT /note="PCI"
FT /evidence="ECO:0000259|PROSITE:PS50250"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 54208 MW; 8D06F8DC6D19E716 CRC64;
MFEMNTAEPM QVDIPPEDNE NNETECYVVE NPTLDLETYA ASYTGFAKLY RLMFVADHCP
SLRLEALKMA ISYVMTTYNV NLYHTLHKKL SEAVASAGLP DIAGSQDIPV LDTIWVESKT
KKAAIKLEKL DTDLKNYKTN SIKESIRRGH DDLGDHYLDC GDLTSALKCY SRARDYCTSG
KHLVMMCLNV VKVSVYLQNW AHVLNYVSKA EATPDFNEIP GKDSNQSILT RLKCAAGLAE
LATKKYKSAA KHFLAASIDH CEYPELMSSN NVAIYGGLCA LATFDRSELQ KQVIVSSSFK
LFLELEPQLR DIIFKFYESK YASCLRLLDE IRDNLLLDMY LAPHINSLYM QIRNRALIQY
FSPYLSADMK LMAAAFNRSV IALEDELMQL ILDGQIQARI DSHNKILYAK DVDQRSTTFE
RSLAMGKEYQ RRTSMLILRA AMLKNQIHVK NIGRDIGPQS GEAPGSSTSL NTRTFDPVPL
//
