ID   Q2FNZ8_METHJ            Unreviewed;       526 AA.
AC   Q2FNZ8;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Signal transduction histidine kinase-like protein {ECO:0000313|EMBL:ABD41037.1};
GN   OrderedLocusNames=Mhun_1294 {ECO:0000313|EMBL:ABD41037.1};
OS   Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 /
OS   JF-1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanospirillaceae; Methanospirillum.
OX   NCBI_TaxID=323259 {ECO:0000313|EMBL:ABD41037.1, ECO:0000313|Proteomes:UP000001941};
RN   [1] {ECO:0000313|Proteomes:UP000001941}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27890 / DSM 864 / NBRC 100397 / JF-1
RC   {ECO:0000313|Proteomes:UP000001941};
RX   PubMed=26744606; DOI=10.1186/s40793-015-0124-8;
RA   Gunsalus R.P., Cook L.E., Crable B., Rohlin L., McDonald E., Mouttaki H.,
RA   Sieber J.R., Poweleit N., Zhou H., Lapidus A.L., Daligault H.E., Land M.,
RA   Gilna P., Ivanova N., Kyrpides N., Culley D.E., McInerney M.J.;
RT   "Complete genome sequence of Methanospirillum hungatei type strain JF1.";
RL   Stand. Genomic Sci. 11:2-2(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP000254; ABD41037.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2FNZ8; -.
DR   STRING; 323259.Mhun_1294; -.
DR   EnsemblBacteria; ABD41037; ABD41037; Mhun_1294.
DR   KEGG; mhu:Mhun_1294; -.
DR   eggNOG; arCOG03642; Archaea.
DR   HOGENOM; CLU_482856_0_0_2; -.
DR   InParanoid; Q2FNZ8; -.
DR   Proteomes; UP000001941; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd18773; PDC1_HK_sensor; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR004010; Double_Cache_2.
DR   InterPro; IPR033480; sCache_2.
DR   Pfam; PF08269; dCache_2; 1.
DR   SMART; SM01049; Cache_2; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Kinase {ECO:0000313|EMBL:ABD41037.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001941};
KW   Transferase {ECO:0000313|EMBL:ABD41037.1};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          244..338
FT                   /note="Single Cache"
FT                   /evidence="ECO:0000259|SMART:SM01049"
FT   DOMAIN          394..474
FT                   /note="Single Cache"
FT                   /evidence="ECO:0000259|SMART:SM01049"
SQ   SEQUENCE   526 AA;  58502 MW;  A9A5008B481FCB6F CRC64;
     MLSALDRITG EISNDLAIIR EENQKSAESL RTIGISGENA TSVLERKLES VHYGHSSLII
     SPDNIVTAAA PVTFSGLIGT DLSYQPETSF ANERQEPVIS NIFYLEEGFY GISISYPIFS
     EGDEYLGYTD VTIRPEEFFR PVIGPFTEQT GYEVFILQTD GMTVYATNEF EVGKNFLTDP
     IYDIPEMRNV SHAVLENEDG TVTYTFWDKN SNRQVPRQAI WDTLSLDNQE WRVAVVRNLE
     EAEKQKGAED QELGSDNLNA SLTNLTQFVQ DAAIFARTTG QESACAAFNN LSGPYVSGDR
     YIFAYTMNST TLALPYQQGL LGKDRPDLFD MNGFSIMPAL IDTAGQGGGF MYGVYPNPDQ
     DFQNQLKIYY VEPVDSDWFI GSGLYIPWIQ AEFGSEEIDA LISRVRQAVR HADLVGKEQA
     IMDFNDLNQS FADGGSYIFA YGYDGTTLAL PHQPELIGTN RMNLTDVYGV PIITQEVRAA
     ERGGGFVYVV YYNPDSGNNE LKLCYVLPAG EDWFVGSGIY LGRGLT
//