ID Q2FY63_STAA8 Unreviewed; 339 AA.
AC Q2FY63;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE SubName: Full=Transcriptional regulator, putative {ECO:0000313|EMBL:ABD30681.1};
GN OrderedLocusNames=SAOUHSC_01602 {ECO:0000313|EMBL:ABD30681.1};
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061 {ECO:0000313|EMBL:ABD30681.1, ECO:0000313|Proteomes:UP000008816};
RN [1] {ECO:0000313|Proteomes:UP000008816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47 {ECO:0000313|Proteomes:UP000008816};
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington D.C
RL (2006).
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DR EMBL; CP000253; ABD30681.1; -; Genomic_DNA.
DR RefSeq; WP_000256338.1; NZ_LS483365.1.
DR RefSeq; YP_500117.1; NC_007795.1.
DR AlphaFoldDB; Q2FY63; -.
DR SMR; Q2FY63; -.
DR STRING; 93061.SAOUHSC_01602; -.
DR PaxDb; 1280-SAXN108_1532; -.
DR GeneID; 3920018; -.
DR KEGG; sao:SAOUHSC_01602; -.
DR PATRIC; fig|93061.5.peg.1459; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_2_9; -.
DR OrthoDB; 43195at2; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IBA:GO_Central.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06294; PBP1_MalR-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008816};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 2..56
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT DOMAIN 3..46
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
SQ SEQUENCE 339 AA; 38390 MW; A186D8359A5A5CCF CRC64;
MVTIKDVALK AGVSPSTVSR VIKGNQRISE ATISKVKKVM EELNYFPNTA ARTLITNQTY
KIGLVLKGSE EPIRLNPFYI NVLLGISETC NQHGYGTQTT VSNNMNDLMD EVYKMIKQRM
VDAFILLYSK ENDPIKQMLI DESMPFIVIG KPTSDIDHQF THIDNDNILA SENLTRHVIE
QGVDELIFIT EKGNFEVSKD RIQGFETIAS QNKINYQIIE TSNEREVIFN YMQNLHTRLK
DPNIKQAIIS LDAMLHLAIL SVLYELNIEI PKDVMTATFN DSYLTEIASP PQTCIDIKPR
MLGQQAGAAI LNILKNKAQD VIELVIIDTE LKIRKSTQR
//
