ID Q2FYJ1_STAA8 Unreviewed; 292 AA.
AC Q2FYJ1;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE RecName: Full=5'-3' exonuclease domain-containing protein {ECO:0000259|SMART:SM00475};
GN OrderedLocusNames=SAOUHSC_01454 {ECO:0000313|EMBL:ABD30541.1};
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061 {ECO:0000313|EMBL:ABD30541.1, ECO:0000313|Proteomes:UP000008816};
RN [1] {ECO:0000313|Proteomes:UP000008816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47 {ECO:0000313|Proteomes:UP000008816};
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington D.C
RL (2006).
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DR EMBL; CP000253; ABD30541.1; -; Genomic_DNA.
DR RefSeq; WP_001133011.1; NZ_LS483365.1.
DR RefSeq; YP_499974.1; NC_007795.1.
DR AlphaFoldDB; Q2FYJ1; -.
DR SMR; Q2FYJ1; -.
DR STRING; 93061.SAOUHSC_01454; -.
DR PaxDb; 1280-SAXN108_1461; -.
DR GeneID; 3919898; -.
DR KEGG; sao:SAOUHSC_01454; -.
DR PATRIC; fig|93061.5.peg.1325; -.
DR eggNOG; COG0258; Bacteria.
DR HOGENOM; CLU_004675_1_5_9; -.
DR OrthoDB; 9806424at2; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000008816}.
FT DOMAIN 3..262
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 292 AA; 33402 MW; 8FDE603B0C080680 CRC64;
MPNKILLVDG MALLFRHFYA TSLHKQFMYN SQGEPTNGIQ GFVRHIFSAI HEIRPTHVAV
CWDMGQSTFR NDMFDGYKQN RSAPPEELIP QFDYVKEISE QFGFVNIGVK NYEADDVIGT
LAQQYSTDND VYIITGDKDL LQCINDNVEV WLIKKGFNIY NRYTLHRFNE EYALEPQQLI
DIKAFMGDTA DGYAGVKGIG EKTAIKLIQQ YQSVENVVEN IDALSAGQRN KINDNLDELY
LSKRLAEIHT QVPIDSEALF EKMSFATTLN HILSICNEHE LHVSGKYISS HF
//
