ID Q2FYS2_STAA8 Unreviewed; 420 AA.
AC Q2FYS2;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE RecName: Full=UmuC domain-containing protein {ECO:0000259|PROSITE:PS50173};
GN OrderedLocusNames=SAOUHSC_01363 {ECO:0000313|EMBL:ABD30458.1};
OS Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=93061 {ECO:0000313|EMBL:ABD30458.1, ECO:0000313|Proteomes:UP000008816};
RN [1] {ECO:0000313|Proteomes:UP000008816}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 8325 / PS 47 {ECO:0000313|Proteomes:UP000008816};
RA Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT "The Staphylococcus aureus NCTC 8325 genome.";
RL (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington D.C
RL (2006).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; CP000253; ABD30458.1; -; Genomic_DNA.
DR RefSeq; WP_000283016.1; NZ_LS483365.1.
DR RefSeq; YP_499890.1; NC_007795.1.
DR AlphaFoldDB; Q2FYS2; -.
DR SMR; Q2FYS2; -.
DR STRING; 93061.SAOUHSC_01363; -.
DR PaxDb; 1280-SAXN108_1380; -.
DR GeneID; 3920068; -.
DR KEGG; sao:SAOUHSC_01363; -.
DR PATRIC; fig|93061.5.peg.1247; -.
DR eggNOG; COG0389; Bacteria.
DR HOGENOM; CLU_012348_5_0_9; -.
DR OrthoDB; 9808813at2; -.
DR Proteomes; UP000008816; Chromosome.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IBA:GO_Central.
DR GO; GO:0042276; P:error-prone translesion synthesis; IBA:GO_Central.
DR GO; GO:0009432; P:SOS response; IBA:GO_Central.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR024728; PolY_HhH_motif.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF11798; IMS_HHH; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008816}.
FT DOMAIN 12..201
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 420 AA; 48427 MW; 15C59908C8A41CE9 CRC64;
MYNYHLLEDR DVLCIDQKSF FASVSCIEKG LDPLETKLAV VADTKRQGSV ILAATPKLKE
LGIKTGSRLF EIPHRNDIYI INPSMRKYLN VSVAISKIAL RYIPPEDLHQ YSIDEFFMDV
TDSYHRFSST VHAFCERLKR EIYEETGIYC TVGIGSNMLL SKIAMDVEAK HSQNGIAEWR
YQDVPTKLWP IQPLRDFWGI NRRTEAKLNK RGIFTIGDLA KYPYKFLKKE FGILGVDMHL
HANGIDQSKV REKHKISNPS ICKSQILMRD YHFDEAKVVM QELIEDVASR VRARKKVART
IHFAFGYSDE GGVHKQYTLK DPTNLEKDIY KVVMHFADKL CNKQALYRTL SISLSQFINE
DERQLSLFED EYQRKRDECL AKTIDQLHLK YGKGIVSKAV SFTEAGTKHG RLGLMAGHKM
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