ID   Q2GI59_EHRCR            Unreviewed;       447 AA.
AC   Q2GI59;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Type IV secretion system protein VirB10 {ECO:0000313|EMBL:ABD44965.1};
GN   Name=virB10 {ECO:0000313|EMBL:ABD44965.1};
GN   OrderedLocusNames=ECH_0042 {ECO:0000313|EMBL:ABD44965.1};
OS   Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Ehrlichia.
OX   NCBI_TaxID=205920 {ECO:0000313|EMBL:ABD44965.1, ECO:0000313|Proteomes:UP000008320};
RN   [1] {ECO:0000313|EMBL:ABD44965.1, ECO:0000313|Proteomes:UP000008320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC CRL-10679 / Arkansas {ECO:0000313|Proteomes:UP000008320};
RX   PubMed=16482227; DOI=10.1371/journal.pgen.0020021;
RA   Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V.,
RA   Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M.,
RA   Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N., Nelson W.,
RA   Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J., Daugherty S.C.,
RA   Davidsen T., Durkin A.S., Gwinn M., Haft D.H., Selengut J.D.,
RA   Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R.,
RA   Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H.;
RT   "Comparative genomics of emerging human ehrlichiosis agents.";
RL   PLoS Genet. 2:208-222(2006).
CC   -!- SIMILARITY: Belongs to the TrbI/VirB10 family.
CC       {ECO:0000256|ARBA:ARBA00010265}.
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DR   EMBL; CP000236; ABD44965.1; -; Genomic_DNA.
DR   RefSeq; WP_006010239.1; NC_007799.1.
DR   AlphaFoldDB; Q2GI59; -.
DR   SMR; Q2GI59; -.
DR   STRING; 205920.ECH_0042; -.
DR   KEGG; ech:ECH_0042; -.
DR   eggNOG; COG2948; Bacteria.
DR   HOGENOM; CLU_041915_0_0_5; -.
DR   OrthoDB; 9807354at2; -.
DR   Proteomes; UP000008320; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd16429; VirB10; 1.
DR   Gene3D; 2.40.128.260; Type IV secretion system, VirB10/TraB/TrbI; 1.
DR   InterPro; IPR005498; T4SS_VirB10/TraB/TrbI.
DR   InterPro; IPR042217; T4SS_VirB10/TrbI.
DR   Pfam; PF03743; TrbI; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008320};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          123..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          363..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..143
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..381
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   447 AA;  48504 MW;  D868945854DEF84C CRC64;
     MSEENQNNQY TEIEENVNVV GVNKGKKFIT IGVMLVGLGF AYYYFFTGKK PDDSLNKPQT
     TEEADIEKLL KESVPPTQEV SPPINIPPQL PELPPLVSPS LPSIPTVEKP KVLEIPKIPK
     IKPKQPVEIK PKPQPQPEPL PKIPLPVQNK IDIAAPIAPI TTGYDKERRA TSMLAVSGGQ
     NVASGTSENG ERESNIDTTI NKMNSIISLQ TTSSPNVVAT KVSNLELTIL QGKIIDVVLE
     TAINSDLQGT LRGIVARDVY AEASNTVMIP KGSRLIGSYS FDASPGKTRV QISWNRVILP
     HGIDITLDSN GTDELGRQGA SGVVDTKIGN ILTSTILLAG VSIATSYATS KIPEINNYPI
     LESDSKEKKD KEKDDTGDKS KSTKTTLPVK ILSQAVDDFS NSIKDIIKKY SNNNPTVYVD
     QGTLLKVFVN KDIVFPKSAV RGIDIVN
//