ID Q2GLA7_ANAPZ Unreviewed; 260 AA.
AC Q2GLA7;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Putative phosphoribosylformylglycinamidine synthase I {ECO:0000313|EMBL:ABD43538.1};
GN OrderedLocusNames=APH_0225 {ECO:0000313|EMBL:ABD43538.1};
OS Anaplasma phagocytophilum (strain HZ).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rickettsiales;
OC Anaplasmataceae; Anaplasma; phagocytophilum group.
OX NCBI_TaxID=212042 {ECO:0000313|EMBL:ABD43538.1, ECO:0000313|Proteomes:UP000001943};
RN [1] {ECO:0000313|EMBL:ABD43538.1, ECO:0000313|Proteomes:UP000001943}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HZ {ECO:0000313|EMBL:ABD43538.1,
RC ECO:0000313|Proteomes:UP000001943};
RX PubMed=16482227; DOI=10.1371/journal.pgen.0020021;
RA Dunning Hotopp J.C., Lin M., Madupu R., Crabtree J., Angiuoli S.V.,
RA Eisen J.A., Seshadri R., Ren Q., Wu M., Utterback T.R., Smith S., Lewis M.,
RA Khouri H., Zhang C., Niu H., Lin Q., Ohashi N., Zhi N., Nelson W.,
RA Brinkac L.M., Dodson R.J., Rosovitz M.J., Sundaram J., Daugherty S.C.,
RA Davidsen T., Durkin A.S., Gwinn M., Haft D.H., Selengut J.D.,
RA Sullivan S.A., Zafar N., Zhou L., Benahmed F., Forberger H., Halpin R.,
RA Mulligan S., Robinson J., White O., Rikihisa Y., Tettelin H.;
RT "Comparative genomics of emerging human ehrlichiosis agents.";
RL PLoS Genet. 2:208-222(2006).
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DR EMBL; CP000235; ABD43538.1; -; Genomic_DNA.
DR RefSeq; WP_011450367.1; NC_007797.1.
DR AlphaFoldDB; Q2GLA7; -.
DR STRING; 212042.APH_0225; -.
DR PaxDb; 212042-APH_0225; -.
DR EnsemblBacteria; ABD43538; ABD43538; APH_0225.
DR GeneID; 56368381; -.
DR KEGG; aph:APH_0225; -.
DR PATRIC; fig|212042.8.peg.236; -.
DR eggNOG; COG0047; Bacteria.
DR HOGENOM; CLU_001031_3_0_5; -.
DR Proteomes; UP000001943; Chromosome.
DR GO; GO:0004642; F:phosphoribosylformylglycinamidine synthase activity; IEA:InterPro.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR010075; PRibForGlyAmidine_synth_PurQ.
DR PANTHER; PTHR10099; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; 1.
DR PANTHER; PTHR10099:SF1; PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE; 1.
DR Pfam; PF13507; GATase_5; 1.
DR PIRSF; PIRSF001586; FGAM_synth_I; 1.
DR SMART; SM01211; GATase_5; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605}.
FT ACT_SITE 99
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 215
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 217
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 260 AA; 28943 MW; 4B8D62C8E1822CED CRC64;
MNVIVLSGYG LNCEEETLFA FQEAGRYLNT NISGKIVHIK ELLSNPKQLA SFNTMVIPGG
FSYGDDTGAG NAYALRLIHG LNEHIRDFMA RDTLLLGICN GCQILLRMLC PNVALVSNDV
GMYQCRWVTV KASNNSVWLD GIDKMYIPVA HGEGKFYAAE DVLQNLETQG DIALRYVNSD
GEYAEGEFPY NPNGSARDIA AITCNSGRAL MMMPHPERAI FFTQRYDWTD IVHGHQNTKG
AVEKYADGFQ IFVNAVRYFS
//
