ID Q2GRS3_CHAGB Unreviewed; 1005 AA.
AC Q2GRS3;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=Peptidase M20 dimerisation domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CHGG_09331 {ECO:0000313|EMBL:EAQ85317.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ85317.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- SIMILARITY: Belongs to the peptidase M20A family.
CC {ECO:0000256|ARBA:ARBA00006247}.
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DR EMBL; CH408034; EAQ85317.1; -; Genomic_DNA.
DR RefSeq; XP_001227258.1; XM_001227257.1.
DR AlphaFoldDB; Q2GRS3; -.
DR STRING; 306901.Q2GRS3; -.
DR GeneID; 4395526; -.
DR VEuPathDB; FungiDB:CHGG_09331; -.
DR eggNOG; KOG2276; Eukaryota.
DR HOGENOM; CLU_008535_1_0_1; -.
DR InParanoid; Q2GRS3; -.
DR OMA; HATVCVD; -.
DR OrthoDB; 177966at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006751; P:glutathione catabolic process; IEA:InterPro.
DR Gene3D; 3.30.70.360; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR017149; GSH_degradosome_Dug2.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR43270; BETA-ALA-HIS DIPEPTIDASE; 1.
DR PANTHER; PTHR43270:SF8; DI- AND TRIPEPTIDASE DUG2-RELATED; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR Pfam; PF00400; WD40; 3.
DR PIRSF; PIRSF037237; Peptidase_WD_repeats_DUG2; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 192..223
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 350..371
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 487..523
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1005 AA; 111376 MW; 44F43419FBD9A151 CRC64;
MAHAAPDLAS CLGSGEKSRK EGDFGAPVEP EVQNQDPPNH ARLIPRNFVW RLAGRPTSST
SSADDVVDGD MAVGVPVLRE RFDPWRHDPL EEELDGQEER CKGCSKIPKA RAAAAVQPPH
DLPPETTPTM PSLQGRELDD GCPDTAPDQL QELRHDGSVL AIAVSDKYIF AGTTKGEITI
WSLGTYQLVQ TLQAHKRSVL CLLLSEDNKY LFSSACEPII GVWCPKTFTR LYEIYSTYDV
GDVFSVAYSP QRETLYLGTQ TQDIQWVNLT DQSRKVPHDS ANHPDKRQHR FFDSRAVGGT
STPRRMEEHY TLIPKATTVL EIDSGAIRQY AHYGWIFCML IAKGPTVLGD PDEEVLVTGG
GDGTIKLWRL SDEGPDHDDG VLGDIEELMT LGDDDSESVM SMAVDGSFLY AGKLQGIIEL
WDLDTKQKLR VIKAHNGNVN TLRMSFGLLW SGATGGSASK HSTVHYGRDK NGLSQNISQK
YQCLNRWKAH DGKILSSAVA THQNDQLFIT GANDNTVRVW RVNGMPTQTE EEIDGSENMM
ITSLREFVSY KTISSRPEFT EDCRKGATYL GSLFKRLGAE VEMLSTGGLH NPIVFAKFNG
KLEPSEKRKR ILFYGHYDVV PADMKGDNWQ TDPFKLEGRD GYLYGRGVSD NKGPIIAAIY
AVSDLLQAKV LDSDIIFVIE GEEESGSRGF QDTIQAHKDL IGNIDYVLLA NSYWLDDEVP
CLTYGLRGVL HATICVDSKH PDLHSGVDGS NLLSEPLTDL TLLLSKLKDS KNHVKIPGFY
DGILPLTDEE DQRYDDIAGI LIRRNPSHGP IEALKRSLMA RWREPNLTIH RYNVSGPDGS
LISSHATANV SVRLVPGQEV EDVITSLRGY LHDQYATFDS DNTLTIRIDN KAEPWLGVPG
NYIFRTLEEA VMRAWGGVSS AEGAAVALPP NATDGEDKPK ARKPLYIREG GSIPPIRYLE
KEFNAPAAHL PCGQATDAAH LDNERLRVMN LMKSREIFST VFRKL
//
