ID Q2H0T6_CHAGB Unreviewed; 1128 AA.
AC Q2H0T6;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=DUF676 domain-containing protein {ECO:0000259|Pfam:PF05057};
GN ORFNames=CHGG_04610 {ECO:0000313|EMBL:EAQ87991.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ87991.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- SIMILARITY: Belongs to the putative lipase ROG1 family.
CC {ECO:0000256|ARBA:ARBA00007920}.
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DR EMBL; CH408032; EAQ87991.1; -; Genomic_DNA.
DR RefSeq; XP_001223824.1; XM_001223823.1.
DR AlphaFoldDB; Q2H0T6; -.
DR STRING; 306901.Q2H0T6; -.
DR ESTHER; chagb-q2h0t6; Duf_676.
DR GeneID; 4392028; -.
DR VEuPathDB; FungiDB:CHGG_04610; -.
DR eggNOG; KOG4372; Eukaryota.
DR HOGENOM; CLU_007367_0_0_1; -.
DR InParanoid; Q2H0T6; -.
DR OMA; WSYIRPT; -.
DR OrthoDB; 1749646at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007751; DUF676_lipase-like.
DR InterPro; IPR044294; Lipase-like.
DR PANTHER; PTHR12482:SF70; LIPASE ROG1-RELATED; 1.
DR PANTHER; PTHR12482; UNCHARACTERIZED; 1.
DR Pfam; PF05057; DUF676; 3.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001056}.
FT DOMAIN 264..304
FT /note="DUF676"
FT /evidence="ECO:0000259|Pfam:PF05057"
FT DOMAIN 360..437
FT /note="DUF676"
FT /evidence="ECO:0000259|Pfam:PF05057"
FT DOMAIN 456..603
FT /note="DUF676"
FT /evidence="ECO:0000259|Pfam:PF05057"
FT REGION 180..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 646..790
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 993..1128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..351
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..372
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..728
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..790
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..869
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 877..918
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1063
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1073..1106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1128 AA; 122526 MW; 8D7C1720DB3F7F4F CRC64;
MLLLHQTGAV RIGEVVRYTV TYTPSADHIL PSPEFLYLRI KNTCAIALRA AFVHGPYTLG
VAAYPSTFKP FEKFDNPRRY GVPEFEPMLK AGAVWNCHLV VPDNIRQSAG EGSSKHGHFG
SGPEHDGDTV TWVVEVSSQV VFSASASVNY EILLARDEKS LNLGSVVPVI GNHAQVAQPG
RVSDFQQSSG SSKHHPAQPK GVFSKAIHLK VEDTAALWNT PQIPGWDDNG WLRAREAEDP
PAPVRPGTEN VNCDEARRQP KQKQKKVHLV VLTHGLHSNL GGDMLFLKES IDATVKQARI
DAKARRARVR AARKSARAGT DSSVDTSENS SQNPTPTPDQ GVQTSGDASD QQGDSDGKED
LTDDEDDEEE DVVVRGFSGN AAKTEKGIKW LGKRLARYIL SMTYPDQPCL PTAKAASDAI
THSLKTGAQK KAIEEAHKHS SVHQATSPGG KRLYKFTKIS FIAHSLGGLV QTYAVAYIQK
HSPQFFDLIE PVNFIALASP FLGLNHENPL YVKFALDFGL VGRTGQDLGL TWRAPTIARN
GWGALMGNLG EHAHKRVYGE HQAESKPLLR ILPTGPAHKA LKKFRNRTVY SNVVNDGIVP
LRTSCLLFLD WQGLGRVEKA RREAGLVETV VGFGWAELTG ANVTTPRLAP WSPVEPEDKD
ESGGTGKTTP TGLGDSHQVP QPPTNAMLED DRQSLRSITS PYRESPSEFQ HLQNSSTTTS
NPLSGLFNFF RSETPKPVPP ASPKVTKIYQ RSQTLKPEQW SALDSAATSS SRVTSGSELT
DEQENMSAPP RTTIFESAGD LLNPKLPPME FIIDPSKRPR TIFHDRVYHP TDIPPPPIKE
RSSSPLTLRR RTPTANSCKT SQSDTSSPLA KPIEDKHTAV SQQSQKPQLP QTPKQTTISV
NSEPLTTQLS SPNTPPGATT DDVIELEIDS SQMRVEEKIA RAYHRGLSWR KVLVKLEPDA
HNNIVVRRTF ANAFGWPVIQ HLVDAHFSDA ATARCPDEDE PNAERAKGVG LAPSTDGRET
KETAQGANAR GEGVRIREGG AGVAAKREED DDGHGEEGDT VPELPRSPKP SPSLPSSAAA
NSNALGVFAS PSSSFDSTTQ AGGGGGGRTP TTPRPPLDRL DSMTMERA
//
