ID Q2H1V2_CHAGB Unreviewed; 799 AA.
AC Q2H1V2;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=DUF803 domain membrane protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CHGG_04244 {ECO:0000313|EMBL:EAQ87625.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ87625.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH408032; EAQ87625.1; -; Genomic_DNA.
DR RefSeq; XP_001223458.1; XM_001223457.1.
DR AlphaFoldDB; Q2H1V2; -.
DR GeneID; 4391755; -.
DR VEuPathDB; FungiDB:CHGG_04244; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_012349_5_2_1; -.
DR InParanoid; Q2H1V2; -.
DR OMA; KNAWWWL; -.
DR OrthoDB; 53219at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF98; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_2G07880); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 524..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..681
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 705..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 86115 MW; AD7EC4EFA91B545C CRC64;
MENAALAIIR HGTDLLNRTE TAAPVQERPP AFKAIGIGLA VGSGAFIGTS FVLKKVGLLR
ANEKYNEVAG EGYGYLKNFY WWAGMILMIV GEGLNFAAYA FTDAILVTPL GALSVVITTV
LSAIFLKERL SMVGKVACFL CIVGSVVIVM NAPHTSSVNN IQEMQGFVIH PAFLTYAGVV
IVGSAVVALW LGPKYGNKNM LVYISICSWV GGLSVVATQG LGAAIIAQAG GTPQFNQWFL
YVLLVFVIGT LLTEIIYLNK ALNLFNAALV TPTYYVYFTS TTIISSAILF RGFKGTPTSI
ITVVNGFLTI CAGVVLLQLS KSAKDVPDTA IFTGDLDQIH TIAEQAQPET EPKADAIRGA
AAIVRRLSSA RQKMELDELK RLREEKLQES LAPVSEDGAP QYEWDGIRRR RTGTISTHRS
GGTPAPTHLA PPTPHLPLGW SHFPTEEELA EANRPVSPGL SSIVGTIRTR ARSVLPGHPE
FRAKTPDASK VQSPMHPVQL TSVAVASSKP ASDDDFTASS RHVQFGQPTR HASDASGDSF
ISALPPTPPP HATARRQFSF QSMFKRNQQS HSRTGSTDTT DRHHGHFRRP SSARPTSSRQ
GPPSRHRRGA TEEETLGLVK GDSNSSQPDA GARSAPALPR HDDVSDEEDE DDASWEGKAL
AKEGAYRDSD GDGDDGKNDR SSGLYGHSIT RGYGPAPGSS PPRSWRRDGE GEIVDDGEKP
GWLERGEDER ERDDRAGARE YEQMRRRFAE QRRASAGNQR GNGDGYGGGG DGGEEEGLDR
PPPPPPHGGT YRSRTGGFI
//
