ID Q2H2J0_CHAGB Unreviewed; 555 AA.
AC Q2H2J0;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=CHGG_04006 {ECO:0000313|EMBL:EAQ87387.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ87387.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; CH408032; EAQ87387.1; -; Genomic_DNA.
DR RefSeq; XP_001223220.1; XM_001223219.1.
DR AlphaFoldDB; Q2H2J0; -.
DR GeneID; 4391718; -.
DR VEuPathDB; FungiDB:CHGG_04006; -.
DR eggNOG; KOG2466; Eukaryota.
DR HOGENOM; CLU_021555_2_0_1; -.
DR InParanoid; Q2H2J0; -.
DR OMA; YEAFAGP; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR012681; NCS1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR NCBIfam; TIGR00800; ncs1; 1.
DR PANTHER; PTHR30618:SF2; ALLANTOIN PERMEASE-RELATED; 1.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 534..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 61212 MW; 242511A708E3F851 CRC64;
MSGKPGVFRR LADKAVVESE PGLTTAQLML TNHDLKPVEP ERRQWGPWNF VGFWIADSFN
INTWMISSSM IVGGLSWWQS WLCVWIGYAI SGCFICLTGR IGATYHIGFP VASRASFGIW
GSLWPVFNRA AMACVWYGVQ SYIGGHCVYL MIRSIWKSWD RETIPNTFAE GSGTTTADYA
SFFIFWFCSL PAIWFPVHQI RHLFTVKAYF VPCAGIAFLI WSVVRAGGIG PIMRQPATKE
GSELAWEFVK GIMSSIANFA TLIVNDPDFS RFAGKPRDAL WSQLFTIPIG FGMTSFIGII
VSSSSTVIYG GEPIWDPLDL LERFINDGGS AQRFGVFVIA AAFSLAQLGT NIAANSVSAG
TDMTALLPRW LNIRRGGYIC AAVGLAMCPY NLLTSSNMFT TYLSAYSVFL SSIAGVMIAD
YYLVRRGFLE VKELYDARRS GPYYFTAGWH WRAYAAYIAG ILINVVGFVG AVGATTVPIG
ATYLYNLNFF CGFGVSAGVY WGLCRVFPIP ATSDKWMEVG DEIVDLRLAY DDRSGSQDDE
EVDAASTVKD VGKTV
//
