ID Q2H6J9_CHAGB Unreviewed; 808 AA.
AC Q2H6J9;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAQ89097.1};
GN ORFNames=CHGG_05716 {ECO:0000313|EMBL:EAQ89097.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ89097.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; CH408031; EAQ89097.1; -; Genomic_DNA.
DR RefSeq; XP_001221811.1; XM_001221810.1.
DR AlphaFoldDB; Q2H6J9; -.
DR STRING; 306901.Q2H6J9; -.
DR GeneID; 4390477; -.
DR VEuPathDB; FungiDB:CHGG_05716; -.
DR eggNOG; KOG1123; Eukaryota.
DR HOGENOM; CLU_008213_0_0_1; -.
DR InParanoid; Q2H6J9; -.
DR OMA; RCQEIDY; -.
DR OrthoDB; 1360679at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd18029; DEXHc_XPB; 1.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR001161; XPB/Ssl2.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR NCBIfam; TIGR00603; rad25; 2.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056}.
FT DOMAIN 371..489
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 541..695
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 719..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 719..737
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 808 AA; 90441 MW; D74A9546967CB6E1 CRC64;
MPPKRKAAPG QGNATKAGRA SAMSTPGPAT PRSLDSSIMS DGDDDFDEDV TEAQREREAL
LSREADDFVN KFTFKGKRLQ GQDDELAGRG RRADAATRLF KKRDFSYLPL KPDHQNRPLW
IDPDSCTVVL ERFNPLAEQA TDFLITIAEP KSRPTFLHEY ALTPHSLYAA VSVGLRPRDI
INTLERFLKT SLPDVVRRKI EDHTKSFGKV KLVLKHNKYF VESVDAEVLQ TLLKDQVIGS
LRVHGSGDIT TSYAPTMGGL VIPGTQNAAG VHQANLRQAE KKPGEGGDAS NEADLFNALN
EEDDDDDKEA VHAFEISDAD VETVQKRCLD IGFPILEEYD FRNDDVNPNL EIDLRPNTQI
RPYQEKSLSK MFGNGRAKSG IIVLPCGAGK TLVGITAACT IKKGVIVLCT SSMSVVQWRQ
EFLKWSNINP DDVAIFTAES KQKFSGSTGI IVTTYSMVTN SRERSHDSKK MMDFLRGREW
GLMLLDEVHV VPAEMFRRGH IAKVQCAEVW CPMPTEFYDE YLRANARMKR TLYAMNPRKF
QACQYLINYH EARGDKIIVF SDELYSLKQY ALKLKKVFIY GGTSQNERMQ VLENFQHNPE
VNTLFLSKIG DTSLDLPEAT CLIQISSHFG SRRQEAQRLG RILRAKRRND EGFNAFFYSL
VSKDTQEMYY SSKRQAFLVD QGYAFKVITQ LANIEKTPDL AFATPLESRE LLQRTLVDNE
RGGEDDVETD DLFGKPGRGG GRKAGNGVRR TAGMLSELAG GQDMAYIEQN KAANKALKGK
GKKGAGGDGQ SKFFKGLQRE KEKSRARG
//
