ID Q2H6S9_CHAGB Unreviewed; 989 AA.
AC Q2H6S9;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=F-box domain-containing protein {ECO:0000259|PROSITE:PS50181};
GN ORFNames=CHGG_05636 {ECO:0000313|EMBL:EAQ89017.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ89017.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH408031; EAQ89017.1; -; Genomic_DNA.
DR RefSeq; XP_001221731.1; XM_001221730.1.
DR AlphaFoldDB; Q2H6S9; -.
DR GeneID; 4390072; -.
DR VEuPathDB; FungiDB:CHGG_05636; -.
DR eggNOG; KOG2922; Eukaryota.
DR HOGENOM; CLU_327797_0_0_1; -.
DR InParanoid; Q2H6S9; -.
DR OMA; RCIVAVQ; -.
DR OrthoDB; 2906343at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF93; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 414..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 699..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 730..749
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 761..779
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..119
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 800..879
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 904..980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..533
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..932
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..961
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 989 AA; 108548 MW; CFF4BD0E8CBE6380 CRC64;
MSTSHTFHTE QTTAAGPAPR PDADAILGVT SYNRADFELP VVTVHPSQHD AVRSTVFQPF
GDKSRHPDFD FDLGRLGRLP FEIVSLICLE LDVTSALRFS HVNRTAREVL TSIREFRHLG
AYALEGLCVL LRTGMAAHVN VLDVYSTLTT QHCSLCGSFG GFMFLPTAAR CCLTCIASAP
AMQVSYLSRV ADATGVEAGA LQKRLPVLHT LPDSRRCIVA VQHALGSLRD SGAGEAEAEA
TARRWPDSLT LRFQAATSLP YLDRMTGEVQ SGVSCKGCQL AFEGDFLDDH LELRDRFYSR
QGFMDHFEEC VPAQKLWGSS QEGTAPAQEP MWTGLGRTFT APGRQRNVMK FIERGTKATA
TARSERNMRL LPPQSPTSLV SRELLAWPAW LPDGDGDGDG DGGPGGPGNE LQNWSSLIGI
ITAICGNVLI ALALNVQRYA HTRLHRKKAQ IRQRARQAIR NAEGGTQGQG AGRYGAAVSP
NGDSHGGSNG YGSGRYSDDG IRGSSETEPL AQSFRSDDSA DGDEEHNHDG KPKVASTYLK
DPYWWLGQVL ITIGEMGNFL AYGFAPASIV SPLGVVALVS NCVIAPIFFK EVFRQRDFWG
VIIAITGAVT VVLSAETEET KLGPHEVWDA ITTMEFEIYL GVSCALIVLL MWLSPKYGHK
TILVDLGLVG LFGGYTVLAT KGVSSMLSST LFGAFTTPVT YVLIFILLFT AIMQVRYVNK
ALQRFDSTQV IPIQFVLFTL SVIIGSAVLY RDFERTTSEQ ALKFIGGCLF TFFGVFLITS
GRSRRDDDDE PTLSDAEGIE ETIGLAEQDR VPPPTPPQPR RRDPPSRSGG SSRTSRVSFS
DIHDAGLPMP RSFPSHPRQS HPLDDEDDGL PDAPLLSNPW QDATTTLATA DYFTTLARTH
LLLRAPTTRR TRPNNRNSPI LIHNTTTNHK TPPRHPTRQR RRNQRRHHPI PIPRPRPRKR
PRPTPHDPAR PREHLPSPAL PHVLALALL
//
