ID Q2H9L4_CHAGB Unreviewed; 623 AA.
AC Q2H9L4;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=FHA domain-containing protein {ECO:0000259|PROSITE:PS50006};
GN ORFNames=CHGG_03090 {ECO:0000313|EMBL:EAQ91155.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ91155.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CH408030; EAQ91155.1; -; Genomic_DNA.
DR RefSeq; XP_001229606.1; XM_001229605.1.
DR AlphaFoldDB; Q2H9L4; -.
DR STRING; 306901.Q2H9L4; -.
DR GeneID; 4389129; -.
DR VEuPathDB; FungiDB:CHGG_03090; -.
DR eggNOG; KOG3872; Eukaryota.
DR HOGENOM; CLU_017542_0_1_1; -.
DR InParanoid; Q2H9L4; -.
DR OMA; VMTENSS; -.
DR OrthoDB; 463769at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:UniProt.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 2.60.200.20; -; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR15067; E3 UBIQUITIN-PROTEIN LIGASE RNF8; 1.
DR PANTHER; PTHR15067:SF8; E3 UBIQUITIN-PROTEIN LIGASE RNF8; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF17123; zf-RING_11; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 259..322
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..209
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..505
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 67060 MW; F49DED2FE4561D15 CRC64;
MFTQPTVSRR PTSTGPGNLV VSPVTAAPAS STPPTRGSRL RGLTYLRNYT QTHILSREHS
AHNNTHAPAV SNPQPATSAP SPPTISTNPW FTSGFTSARH DHSTTTPALD NNDSSNINND
NNNNYNPTSS STRTNRFSHL VPTLGQPLRR SPDSSNERGP SGPATGISSE LRAADAPPIP
FPSSKNGSRI ADGNRQTTGE MTRARSATTG DALTRHDGGG GLDTLPSIRF STFVDPRATR
PSLKFGPISR TLPSGREVIR VGRYSERDSQ PNIPVNAPSA APVGFKSKVV SRRHCEFWYE
EGKWYIKDVK SSSGTFLNHI RLSPPGTESK PYPVNDGDIV QLGIDFKGGE EMIFRCVKMR
LELNRGWQNK LNTFNIAPCQ CLFVAPCSHT WHYKCIRSLL SSPSFPIFIC PNCRAAADLE
AEVEDPEEWE QLSDEGAVAP QGALLQPPLV DPNSQNSNSP SAPRKSRESV RSTRLFAAQQ
QQQLQPAEDS NMDLLMSSSP PRQESPPQLD GAVTLADPNL LSHTLSTPMP IPSPAQRTLP
NGRRETRTPS PTGAPVANGH EGPITPRNDA GPWVFDGSGV RLSSESARPA GAALSQGGEV
PASSIEAAVQ AAGARLVREN DDP
//
