ID   Q2HBH8_CHAGB            Unreviewed;      1112 AA.
AC   Q2HBH8;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN   ORFNames=CHGG_02426 {ECO:0000313|EMBL:EAQ90491.1};
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ90491.1, ECO:0000313|Proteomes:UP000001056};
RN   [1] {ECO:0000313|Proteomes:UP000001056}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC   {ECO:0000313|Proteomes:UP000001056};
RX   PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH408030; EAQ90491.1; -; Genomic_DNA.
DR   RefSeq; XP_001228942.1; XM_001228941.1.
DR   AlphaFoldDB; Q2HBH8; -.
DR   GeneID; 4389169; -.
DR   VEuPathDB; FungiDB:CHGG_02426; -.
DR   eggNOG; KOG4177; Eukaryota.
DR   HOGENOM; CLU_000288_34_23_1; -.
DR   InParanoid; Q2HBH8; -.
DR   OMA; GHEMMVQ; -.
DR   OrthoDB; 2479680at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46224; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR   PANTHER; PTHR46224:SF6; IQ MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF12796; Ank_2; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 11.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 2.
DR   PROSITE; PS50088; ANK_REPEAT; 3.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          216..369
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REPEAT          741..773
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          774..806
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          866..898
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ   SEQUENCE   1112 AA;  122319 MW;  DF623F1D2A844662 CRC64;
     MADVGTIVGI ISLGIQVADG LVKYYTAYKD RESETAHTVK RLTHLLGILE VLRKNLVDRS
     FQPDETSLLE TIKSSVGDCE DLIKELEKET EKFTQSASGS VTAAVRVTGR RLAYPFRQST
     LQKLDEDIAE ICANLTLALQ VLQQQDIGSV QDEIQDTKAL LELVRADQIS TEIKNWLNAP
     DASINYNDAC KKKYPGTGLW FIKSPQFSTW LQTANSFLWL KGFAGCGKSV LSSTIIQHTL
     RHRRSNPAIG IAFFYFTFND DAKQDTSAML RALILQLAPQ LQLHTTTTTT NNKDALLPRL
     HQNYRGGTPP DPALLDTLHQ LITRFDDVYI ILDALDESPR HKHREDLLQA LAEMRSWPGP
     ELHLLVTSRD EQDIREELVL EEEEVVVLKG GKVDADIAAF VAGHLKDNRR LRKWERFHGR
     IEEALTEGAK GVFRWVECQF SALEACPGSK TRLDALLGSL PRTLDKTYER MLYNIEEESV
     DDARRILTLL CTAKRPLKVE ELIDGIAVEL GDNAKFNEDS RLMNQDDIRH ICPGFIEVDL
     NNEDRGPTVR IAHYSVQEYL ESDRIVASGT ARFSVRRKEA NTEVASICLI YLMDEALCKA
     CMTETWVFGY DAKYPLAAYA ASSWADHYHE GDPLDPQLHR LALALFHDDE NALASWANIY
     KWAGYKRDGL GDRILTPLYL AARLGLDPVV RVLADEATSS PTRPRKYYFE SALITAATFG
     HASTVALLLT HSSAAINHLG FEGTALHLAA RHGHLAVVDT LLAHGADIEA RDYRGKSALY
     DAAAGGKDEV VRLLLERGAE IEPAGTYDTP LECAAAGGRE AVVAMLLDRG LDPNRGRYAR
     PLEVAREHPA VVRLLLDRGA DVDLGTPTRP LALACSGGAV GVVAVLLERG ADVEKAGGWA
     GLMERAVGNS DPKVVDLLLE HGADAKGEEG CHVTPLEAAA GLWNATAVMR RLLDAGARVN
     IGKEMTPLEK AAKKSSLPTA RLLLERRADP NLGIQMTPLE AAADEMSESM MTLLINHGAD
     VNKGLQMTPL EVLVQKEVIP FRLVELLVQM GADVNKGFKI NPSEVALRHG YNLEGIVVIP
     GEIEVESIEG AGTLGEKKEM VIVIGPKAAN SS
//