ID Q2HEV0_CHAGB Unreviewed; 517 AA.
AC Q2HEV0;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=CHGG_01254 {ECO:0000313|EMBL:EAQ93019.1};
OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS NRRL 1970) (Soil fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ93019.1, ECO:0000313|Proteomes:UP000001056};
RN [1] {ECO:0000313|Proteomes:UP000001056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC {ECO:0000313|Proteomes:UP000001056};
RX PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL Genome Announc. 3:E0002115-E0002115(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH408029; EAQ93019.1; -; Genomic_DNA.
DR RefSeq; XP_001220475.1; XM_001220474.1.
DR AlphaFoldDB; Q2HEV0; -.
DR GeneID; 4386869; -.
DR VEuPathDB; FungiDB:CHGG_01254; -.
DR eggNOG; KOG2533; Eukaryota.
DR HOGENOM; CLU_001265_0_1_1; -.
DR InParanoid; Q2HEV0; -.
DR OMA; YPRREQQ; -.
DR OrthoDB; 1821734at2759; -.
DR Proteomes; UP000001056; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR43791; PERMEASE-RELATED; 1.
DR PANTHER; PTHR43791:SF58; TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04470)-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..136
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..517
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 517 AA; 56658 MW; 6A11F2C56D47F4D8 CRC64;
MSHSVSPEPA TSLNQTQLES KPHTVQVNSD PDPTDDAVFK IDQDAAIGSA PTTDTMAVAV
DDALERRIRL RVDLRLCTIA GILCSLNLLD SGVLSSAAVT SMLSDLGLDQ GNRFSVSIFI
FTISSIVFQL PSTIAVRILG PRLHFTLITL AFGIITLCTG FVRTWQQMIV LRILLGAAMA
GVFPGLSYLI STWYPRREQQ LRFAFMQSGE VIILATGSLV NYGLNGLDGR RGLEGWRWMF
VVQGLCTCVI GLVTYWWMVD FPENSHNSFR FLTAEEAGIV SKRIQTDRGD LVAQDFAIAK
VLVHAKDPKI WAFASLFFIQ NLVSTSLAYF VPIILENGLG YSPDTSIILS APPYYYAVVP
VLISSYFADR FRIRGPVIAF NALCLITGFA VLGFAQNSGA RYFGVFLATG AYVGNWAALT
AYQANNVVGA FNGAGGIAGS FIVRNFEAPF YTTAVWVSIG YDRIFLECHV PLLMVPSSHI
LMISVVAVLS VHFYLANKSQ SKRSGVLENT EGFRFTY
//
