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Database: UniProt
Entry: Q2HF49_CHAGB
LinkDB: Q2HF49_CHAGB
Original site: Q2HF49_CHAGB 
ID   Q2HF49_CHAGB            Unreviewed;       631 AA.
AC   Q2HF49;
DT   21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2006, sequence version 1.
DT   05-JUN-2019, entry version 58.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAQ92920.1};
GN   ORFNames=CHGG_01155 {ECO:0000313|EMBL:EAQ92920.1};
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC
OS   6347 / NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae;
OC   Chaetomium.
OX   NCBI_TaxID=306901 {ECO:0000313|EMBL:EAQ92920.1, ECO:0000313|Proteomes:UP000001056};
RN   [1] {ECO:0000313|Proteomes:UP000001056}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970
RC   {ECO:0000313|Proteomes:UP000001056};
RX   PubMed=25720678; DOI=10.1128/genomeA.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium
RT   globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC   -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC       {ECO:0000256|RuleBase:RU003968}.
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DR   EMBL; CH408029; EAQ92920.1; -; Genomic_DNA.
DR   RefSeq; XP_001220376.1; XM_001220375.1.
DR   STRING; 38033.XP_001220376.1; -.
DR   EnsemblFungi; EAQ92920; EAQ92920; CHGG_01155.
DR   GeneID; 4387477; -.
DR   eggNOG; KOG1238; Eukaryota.
DR   eggNOG; COG2303; LUCA.
DR   InParanoid; Q2HF49; -.
DR   OrthoDB; 798314at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR012132; GMC_OxRdtase.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   PROSITE; PS00623; GMC_OXRED_1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001056};
KW   FAD {ECO:0000256|PIRSR:PIRSR000137-2, ECO:0000256|RuleBase:RU003968};
KW   Flavoprotein {ECO:0000256|RuleBase:RU003968};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001056};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    631       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004209435.
FT   DOMAIN      117    140       GMC_OxRdtase_N. {ECO:0000259|PROSITE:
FT                                PS00623}.
FT   NP_BIND      47     48       FAD. {ECO:0000256|PIRSR:PIRSR000137-2}.
FT   REGION      343    366       Disordered. {ECO:0000256|MobiDB-lite:
FT                                Q2HF49}.
FT   ACT_SITE    565    565       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR000137-1}.
FT   ACT_SITE    608    608       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000137-1}.
FT   BINDING     119    119       FAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000137-2}.
FT   BINDING     278    278       FAD; via amide nitrogen and carbonyl
FT                                oxygen. {ECO:0000256|PIRSR:PIRSR000137-
FT                                2}.
FT   BINDING     563    563       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR000137-2}.
SQ   SEQUENCE   631 AA;  68684 MW;  12EC9E73AEA9FCBB CRC64;
     MKIASSLSCL FAVLRLTFAN PQATGNVKRQ GSQLLDSYDF VIAGGGTSGL TVADRLTEAF
     PDKTVLVVEY GEVENARGIF DPPMTIWGGS SNAASGWLLN STPSPELNNA TALVMVGKVV
     GGSSAINGQF FDRGSRFDYD AWDRLQGGSP ESRMKGINWS WDGIYPFFRK SVTFTPPPEA
     VARKYNYTWD TSAFENVTPI HASFPPFLWG DHSVGRDAWE EMGIWRAEEC ANGDKEGLCW
     IPISQHPITA RRSYSGIGHY ADVVADRPNY HLLVKHQVAR VVYPEWNTKS GPPLVEVRPL
     DGGPLFNISV KNEVILSSGV FGTPAILQRS GIHHRDYLTC LNPQLSKRHS HPRQTRSRSL
     STPSPSDMLN ATFAAETAAG FNQTPAQGPY TLAMSNSAIW VSLPNITIDY PTIMDAIRAQ
     NTSPKHRHPP PPPAYNADPT LIAGYRAQLS QLAQLYANPH SPSLESAWAT GTSPAAILLH
     PLSRGTARLN GTHPFEPPVL DYRSASNPVD MALHLAHTRY LRRMTRTDTL RGLGAVEVGP
     GDEAAADEER LTAYVRQNTV QSYMHPCCTA AMLPRARGGV VGSDLSVYGA AGLRVVDMSV
     LPMLPAAHLS ATAYAVGEKA ADIIIKRWKA E
//
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