ID Q2HVU4_MEDTR Unreviewed; 443 AA.
AC Q2HVU4; A0A0C3WDL5; G7L0K1;
DT 21-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=ADP-ribosylation factor GTPase-activating protein AGD10 {ECO:0000313|EMBL:AES81716.2};
DE SubName: Full=Arf GTPase activating protein {ECO:0000313|EMBL:ABD32193.1, ECO:0000313|EMBL:RHN48358.1};
GN Name=11419488 {ECO:0000313|EnsemblPlants:AES81716};
GN OrderedLocusNames=MTR_7g099830 {ECO:0000313|EMBL:AES81716.2};
GN ORFNames=MtrDRAFT_AC148343g9v2 {ECO:0000313|EMBL:ABD32193.1},
GN MtrunA17_Chr7g0262921 {ECO:0000313|EMBL:RHN48358.1};
OS Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX NCBI_TaxID=3880 {ECO:0000313|EMBL:ABD32193.1};
RN [1] {ECO:0000313|EMBL:ABD32193.1}
RP NUCLEOTIDE SEQUENCE.
RA Town C.D.;
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABD32193.1}
RP NUCLEOTIDE SEQUENCE.
RG The International Medicago Genome Annotation Group;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ACJ85591.1}
RP NUCLEOTIDE SEQUENCE.
RA Moskal W., Chan A., Cheung F., Xiao Y., Town C.D.;
RT "Medicago truncatula full length cdna cloning project.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AES81716.2, ECO:0000313|Proteomes:UP000002051}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A17 {ECO:0000313|EMBL:AES81716.2}, and cv. Jemalong A17
RC {ECO:0000313|EnsemblPlants:AES81716,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=22089132; DOI=10.1038/nature10625;
RA Young N.D., Debelle F., Oldroyd G.E., Geurts R., Cannon S.B., Udvardi M.K.,
RA Benedito V.A., Mayer K.F., Gouzy J., Schoof H., Van de Peer Y., Proost S.,
RA Cook D.R., Meyers B.C., Spannagl M., Cheung F., De Mita S.,
RA Krishnakumar V., Gundlach H., Zhou S., Mudge J., Bharti A.K., Murray J.D.,
RA Naoumkina M.A., Rosen B., Silverstein K.A., Tang H., Rombauts S.,
RA Zhao P.X., Zhou P., Barbe V., Bardou P., Bechner M., Bellec A., Berger A.,
RA Berges H., Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R.,
RA Deshpande S., Dai X., Doyle J.J., Dudez A.M., Farmer A.D., Fouteau S.,
RA Franken C., Gibelin C., Gish J., Goldstein S., Gonzalez A.J., Green P.J.,
RA Hallab A., Hartog M., Hua A., Humphray S.J., Jeong D.H., Jing Y.,
RA Jocker A., Kenton S.M., Kim D.J., Klee K., Lai H., Lang C., Lin S.,
RA Macmil S.L., Magdelenat G., Matthews L., McCorrison J., Monaghan E.L.,
RA Mun J.H., Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R.,
RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., Sallet E.,
RA Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., Schiex T.,
RA Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., Singer S.R.,
RA Sinharoy S., Sterck L., Viollet A., Wang B.B., Wang K., Wang M., Wang X.,
RA Warfsmann J., Weissenbach J., White D.D., White J.D., Wiley G.B.,
RA Wincker P., Xing Y., Yang L., Yao Z., Ying F., Zhai J., Zhou L., Zuber A.,
RA Denarie J., Dixon R.A., May G.D., Schwartz D.C., Rogers J., Quetier F.,
RA Town C.D., Roe B.A.;
RT "The Medicago genome provides insight into the evolution of rhizobial
RT symbioses.";
RL Nature 480:520-524(2011).
RN [5] {ECO:0000313|EMBL:AFK49050.1}
RP NUCLEOTIDE SEQUENCE.
RA Krishnakumar V., Cheung F., Xiao Y., Chan A., Moskal W.A., Town C.D.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:AES81716.2, ECO:0000313|Proteomes:UP000002051}
RP GENOME REANNOTATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES81716,
RC ECO:0000313|Proteomes:UP000002051};
RX PubMed=24767513; DOI=10.1186/1471-2164-15-312;
RA Tang H., Krishnakumar V., Bidwell S., Rosen B., Chan A., Zhou S.,
RA Gentzbittel L., Childs K.L., Yandell M., Gundlach H., Mayer K.F.,
RA Schwartz D.C., Town C.D.;
RT "An improved genome release (version Mt4.0) for the model legume Medicago
RT truncatula.";
RL BMC Genomics 15:312-312(2014).
RN [7] {ECO:0000313|EnsemblPlants:AES81716}
RP IDENTIFICATION.
RC STRAIN=cv. Jemalong A17 {ECO:0000313|EnsemblPlants:AES81716};
RG EnsemblPlants;
RL Submitted (APR-2015) to UniProtKB.
RN [8] {ECO:0000313|EMBL:RHN48358.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:RHN48358.1};
RA Pecrix Y., Gamas P., Carrere S.;
RT "Whole-genome landscape of Medicago truncatula symbiotic genes.";
RL Nat. Plants 0:0-0(2018).
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DR EMBL; AC148343; ABD32193.1; -; Genomic_DNA.
DR EMBL; BT052929; ACJ85591.1; -; mRNA.
DR EMBL; CM001223; AES81716.2; -; Genomic_DNA.
DR EMBL; BT149256; AFK49050.1; -; mRNA.
DR EMBL; PSQE01000007; RHN48358.1; -; Genomic_DNA.
DR RefSeq; XP_003625498.2; XM_003625450.2.
DR AlphaFoldDB; Q2HVU4; -.
DR STRING; 3880.Q2HVU4; -.
DR iPTMnet; Q2HVU4; -.
DR PaxDb; 3880-AES81716; -.
DR EnsemblPlants; AES81716; AES81716; MTR_7g099830.
DR GeneID; 11419488; -.
DR Gramene; AES81716; AES81716; MTR_7g099830.
DR KEGG; mtr:11419488; -.
DR eggNOG; KOG0704; Eukaryota.
DR HOGENOM; CLU_044516_1_0_1; -.
DR OrthoDB; 389572at2759; -.
DR Proteomes; UP000002051; Chromosome 7.
DR Proteomes; UP000265566; Chromosome 7.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd08830; ArfGap_ArfGap1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR044519; ARF_GAP_AGD6/7.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR47021; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD6-RELATED; 1.
DR PANTHER; PTHR47021:SF4; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD7; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 2: Evidence at transcript level;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000002051};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 4..120
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 128..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..401
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 443 AA; 48367 MW; A7E6D9FAE676A011 CRC64;
MAASRRLREL QSEPSNKICV DCSQKNPQWA SVSYGVFMCL ECSGKHRGLG VHISFVRSVT
MDSWSDLQIK KMEAGGNRNL NTFLSQYGIS KETDIITKYN SNAASIYRDR IQAIAEGRSW
RDPPVVKENA STRAGKGKPP LAAASNGGGW DDNWDNDDGD SYGYGSRGGG DIRRNQSTGD
VIGFVGNGVT PSSRSKSTED IYTRTQLEAS AANKEGFFAK KMAENESRPE GLPPSQGGKY
VGFGSSPGPA QRISPQNDYL SVVSEGIGKL SMVAQSATKE ITAKVKDGGY DHKVNETVNI
VTQKTSEIGQ RTWGIMKGVM ALASQKVEEF TKDYPDGNSD NWPRNENDRH DFNQENKGWN
SSTSTREGQP SSGGQTNTYH SNSWDDWDNQ DTRKEVPAKG SAPHNNDDWA GWDDAKDDDD
EFDDKSFGNN GTSGSGWTGG GFH
//
