ID Q2IQG1_ANADE Unreviewed; 767 AA.
AC Q2IQG1;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:ABC81044.1};
GN OrderedLocusNames=Adeh_1270 {ECO:0000313|EMBL:ABC81044.1};
OS Anaeromyxobacter dehalogenans (strain 2CP-C).
OC Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC Anaeromyxobacteraceae; Anaeromyxobacter.
OX NCBI_TaxID=290397 {ECO:0000313|EMBL:ABC81044.1, ECO:0000313|Proteomes:UP000001935};
RN [1] {ECO:0000313|Proteomes:UP000001935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2CP-C {ECO:0000313|Proteomes:UP000001935};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R.,
RA Gilna P., Kiss H., Schmutz J., Larimer F., Land M., Kyrpides N.,
RA Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R.,
RA Zhulin I.B., Loeffler F.E., Richardson P.;
RT "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000251; ABC81044.1; -; Genomic_DNA.
DR RefSeq; WP_011420327.1; NC_007760.1.
DR AlphaFoldDB; Q2IQG1; -.
DR STRING; 290397.Adeh_1270; -.
DR KEGG; ade:Adeh_1270; -.
DR eggNOG; COG0658; Bacteria.
DR eggNOG; COG2333; Bacteria.
DR HOGENOM; CLU_010363_2_1_7; -.
DR OrthoDB; 9790149at2; -.
DR Proteomes; UP000001935; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001935};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 213..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 253..270
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 517..710
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 767 AA; 77253 MW; AC4E8705AD360B57 CRC64;
MTRRPLLLPA LGLALGVGLG LEGATVPPAA LGALPLALLP RLAPLAFAAA GWLAAASARV
PPAAPPDGAV LVRGRVVGAP DRLEDRLRFP VRTAGGALLE AWAEPTPWPL ALGDEVLFRA
TLRAPAGRRN PGGRDPGDRL RSGGAALVAL ADGPVVRTAA PAAASRLERA RDRLAEAAGR
WLPPDQAALV RAIGTGDRAA LDPEASASFA RSGLAHVLAV SGFHLVVVAF GLERLLRALL
LRADAVAARA DPRRVAAALT LPCALLYALA TGAGAPVVRA ALAAAVILAG ALLDRAADPL
NSLALAALAI LAAEPAALLD ASFQLSFAAV AGLALWATPL RGALPVARPA PGSWRARLLE
PFLSGAAATV AATLATAPVL AFHFRQLPLL GVAANVAAIP LGAALTALAA LAAVAAAASP
LAAAPFLLAA GPLAAALRAV SDAAAAPRWG AVGLASPGGW AAAAATALVL GVPALPRRLR
LGAGALAAAL LLLPGPLRAA AARARGGLEV IFVSVGQGDA ALLRLPDGSA VLVDGGGAAG
GGPDPGARDL VPLLRDLGVR RLEAVFVSHP HPDHVLGLEA VARAFPVARA YSNGDRGDGP
AREVLAALAP VTLAPGEAWE RAGVRFEALG GDRTPFAAND ASLVLRATYG ATTFLFPGDV
EAAGEAAAVA RGGLRADVVK IPHHGSRTSS TEPFVRAVRA RWAVACLGAH NRFGFPHPEP
LARWAAAGAE VLRTDEGAVR FLSDGRAVRR VEAGSVLDAL ATWREQP
//
