ID   Q2IV77_RHOP2            Unreviewed;       389 AA.
AC   Q2IV77;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=Alcohol dehydrogenase superfamily, zinc-containing {ECO:0000313|EMBL:ABD07883.1};
GN   OrderedLocusNames=RPB_3187 {ECO:0000313|EMBL:ABD07883.1};
OS   Rhodopseudomonas palustris (strain HaA2).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Rhodopseudomonas.
OX   NCBI_TaxID=316058 {ECO:0000313|EMBL:ABD07883.1, ECO:0000313|Proteomes:UP000008809};
RN   [1] {ECO:0000313|EMBL:ABD07883.1, ECO:0000313|Proteomes:UP000008809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HaA2 {ECO:0000313|EMBL:ABD07883.1,
RC   ECO:0000313|Proteomes:UP000008809};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A.,
RA   Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris HaA2.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR   EMBL; CP000250; ABD07883.1; -; Genomic_DNA.
DR   RefSeq; WP_011442067.1; NC_007778.1.
DR   AlphaFoldDB; Q2IV77; -.
DR   STRING; 316058.RPB_3187; -.
DR   KEGG; rpb:RPB_3187; -.
DR   eggNOG; COG1063; Bacteria.
DR   HOGENOM; CLU_026673_11_3_5; -.
DR   OrthoDB; 9773078at2; -.
DR   Proteomes; UP000008809; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          8..387
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   389 AA;  42105 MW;  2EF1C504655F0E0B CRC64;
     MKALTWHGKS DIRCESVPDP KIEHGRDAII RVTACAICGS DLHLFDGVMP SMKSGDVLGH
     ETMGEVVEVG ADNKALKVGD RVVVPFTISC GECFFCKRGF YSGCERSNPN AEQAAKLWGH
     SPAGLFGYSH LLGGFAGGQA EYLRVPYADV GPIKVPDGMT DEQALFLSDI FPTGFMAADF
     CNLKGGETVA IWGCGPVGQF AIKSAFLLGA ERVIAIDTVP ERLEMARASG AITIDFRNED
     VYDRIQDLTH GRGADACIDA VGTEPDTASG FDAIVDRIKV ATFMGTDRPH VLRQAIHCCR
     NFGTVSIVGV YGGLLDNIPM GSAINRGLTF RMAQTPVQHY LPQLLARIEK GEIDPTFVIT
     HRATLEDGPE LYKTFRDKQD GCIKVVMKP
//