ID Q2J7D2_FRACC Unreviewed; 1302 AA.
AC Q2J7D2;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 114.
DE RecName: Full=Lipopolysaccharide export system ATP-binding protein LptB {ECO:0000256|ARBA:ARBA00017803};
GN OrderedLocusNames=Francci3_3456 {ECO:0000313|EMBL:ABD12810.1};
OS Frankia casuarinae (strain DSM 45818 / CECT 9043 / HFP020203 / CcI3).
OC Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX NCBI_TaxID=106370 {ECO:0000313|EMBL:ABD12810.1, ECO:0000313|Proteomes:UP000001937};
RN [1] {ECO:0000313|EMBL:ABD12810.1, ECO:0000313|Proteomes:UP000001937}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45818 / CECT 9043 / CcI3
RC {ECO:0000313|Proteomes:UP000001937};
RX PubMed=17151343; DOI=10.1101/gr.5798407;
RA Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA Benson D.R.;
RT "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT reflect host range and host plant biogeography.";
RL Genome Res. 17:7-15(2007).
CC -!- FUNCTION: Part of the ABC transporter complex LptBFG involved in the
CC translocation of lipopolysaccharide (LPS) from the inner membrane to
CC the outer membrane. Probably responsible for energy coupling to the
CC transport system. {ECO:0000256|ARBA:ARBA00024818}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. The LptBFG transporter is composed of two ATP-binding proteins
CC (LptB) and two transmembrane proteins (LptF and LptG).
CC {ECO:0000256|ARBA:ARBA00026081}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004515}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004515}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004515}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Outer membrane
CC lipopolysaccharide export (TC 1.B.42) family.
CC {ECO:0000256|ARBA:ARBA00010865}.
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DR EMBL; CP000249; ABD12810.1; -; Genomic_DNA.
DR RefSeq; WP_011437835.1; NC_007777.1.
DR STRING; 106370.Francci3_3456; -.
DR KEGG; fra:Francci3_3456; -.
DR eggNOG; COG0410; Bacteria.
DR eggNOG; COG0411; Bacteria.
DR eggNOG; COG0559; Bacteria.
DR eggNOG; COG4177; Bacteria.
DR HOGENOM; CLU_006313_4_1_11; -.
DR Proteomes; UP000001937; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:InterPro.
DR CDD; cd03224; ABC_TM1139_LivF_branched; 1.
DR CDD; cd06582; TM_PBP1_LivH_like; 1.
DR CDD; cd06581; TM_PBP1_LivM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001851; ABC_transp_permease.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR032823; BCA_ABC_TP_C.
DR InterPro; IPR043428; LivM-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45772; CONSERVED COMPONENT OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS-RELATED; 1.
DR PANTHER; PTHR45772:SF10; LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF12399; BCA_ABC_TP_C; 1.
DR Pfam; PF02653; BPD_transp_2; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:ABD12810.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001937};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 528..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 571..594
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 614..636
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 648..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 682..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 731..754
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 749..995
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1058..1279
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1278..1302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1302 AA; 134976 MW; 4BDF01577D961BE0 CRC64;
MNDVMGYALL SLGTGALYAL VASGVVVIAR GAGVLNLAQG ALLAWAAYAF HGLHAGWGLP
LGLAAPLAVL STTVIGVVFH LLVMRPLREA TSLLRLMATL GLLIILQSLL TLMFAGAVRT
SPTVLPTGRI TLFDEPVGVS VFVRLAVVAV LVAGLWAVFR FTTVGLAATV AAENLRAAAT
FGWSADTVAA AAWGAGSALA GLGGVLLAPL QNPLSSANLL LLIVPALAVA LVARFRSFPM
VLAGGLALGV VEVETQFQLV AEHPWWRGVD RAVPLAVIVF YLAIRGQGIP ERGHLAERQP
ALGSGRVHPR ALAVTVAATL AAIWWLLPVD WVDAIDANAL WALVILSVVV LVGFTGQLSL
AQLAFSGIAA LIAGRLVATR GWPLEAAMLV GVAGTAAVGL LFALPALRTR GLQLAVVTLG
LGTAVDALLF QRGYHSPAPR SAGSIGSLFG DLASPEGTVV GRQTFLGIEL DKVANPRGFA
TVSVLAFVLV ALAVANLRRG RAGRRLIAVR TNERAAAALG ISVVGAKLYA FALSAAIAGF
GGVLYAFYVY GERGNIDYGG GAFAPFSSIM LIAYAVLGGV GWVSGAFAGA TMAAGALATR
LGGWVGDLLA RLGVLLRVVV AALAGLLGLA AGASLVSAPR PRRRLGAAAR YAPWAVAAVA
ALVAAVFGGW VRDWLAELDR YVPLIGGIVL VVVLSRSGGG MAPENARTAR LLHDRVPAAA
ARRRRRDAAR LARLLGAPPA ALPAVPAVLS VWGLTVRFGA VTAVRSVDLR VEPGQIVGMI
GPNGAGKTTV IDAITGYTPS SVTSVTSMTL GGVRLDRLPA HRRARAGISR SFQNLELFDD
LTVIENIQAA SDRRDTRAYL TDLLFPRGRP LEPAAVAAVD AFGLRDDLLR TVAELPYGRR
RLLAIARAVA ARPAVLLLDE PCAGLDESES AEVAGLLRRL ADDWGLGILL NEHDMDVVMG
VCDRVVVLDA GERIAEGTPE RVRDDPRVRV ACLGEAAVPA RPAVSWTRPA VSWTRRAVSW
TRRAVSWTRP AGPSAGGTGD RVADRTDPAR FAAGPAVLAA RGLSAGYGNG PVVRDLNLEV
HAGEVVTLLG PNGAGKTTTL LALAGAIPSA GGEVLLAGAV TTAALHERCR RGLSLVPEER
SVIMDLTVRE NLRVGRCDPD LALAVFPELA EHLDRRAGLL SGGQQQMVTL ARALARRPTV
LLADELSLGL APRVVDRLLA AVRAAADDGL AVILVEQHVR SALSIADRVH VLRHGALAWS
GTAAQARADR ETLLGAYLSP GRPADSGNGA PSGNGALSGP RA
//
