ID   Q2JA60_FRACC            Unreviewed;       495 AA.
AC   Q2JA60;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 89.
DE   SubName: Full=Tryptophan halogenase {ECO:0000313|EMBL:ABD11832.1};
GN   OrderedLocusNames=Francci3_2465 {ECO:0000313|EMBL:ABD11832.1};
OS   Frankia casuarinae (strain DSM 45818 / CECT 9043 / HFP020203 / CcI3).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=106370 {ECO:0000313|EMBL:ABD11832.1, ECO:0000313|Proteomes:UP000001937};
RN   [1] {ECO:0000313|EMBL:ABD11832.1, ECO:0000313|Proteomes:UP000001937}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45818 / CECT 9043 / CcI3
RC   {ECO:0000313|Proteomes:UP000001937};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA   Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA   Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA   Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA   Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA   Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA   Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- SIMILARITY: Belongs to the flavin-dependent halogenase family.
CC       Bacterial tryptophan halogenase subfamily.
CC       {ECO:0000256|ARBA:ARBA00038396}.
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DR   EMBL; CP000249; ABD11832.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2JA60; -.
DR   STRING; 106370.Francci3_2465; -.
DR   KEGG; fra:Francci3_2465; -.
DR   eggNOG; COG0644; Bacteria.
DR   HOGENOM; CLU_024648_4_0_11; -.
DR   PhylomeDB; Q2JA60; -.
DR   Proteomes; UP000001937; Chromosome.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   Gene3D; 3.30.9.100; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006905; Flavin_halogenase.
DR   PANTHER; PTHR43747:SF1; FAD-BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43747; FAD-BINDING PROTEIN; 1.
DR   Pfam; PF04820; Trp_halogenase; 2.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001937}.
SQ   SEQUENCE   495 AA;  54505 MW;  0B9B3D215C676BB2 CRC64;
     MTDSAEFDVV VVGGGPAGST LAALVAMQGH RVLVLEKEHF PRYQIGESLL PSTIHGVCRL
     TGAADELAKA GFPLKRGGTF RWGATPEPWT FAFSVSSRMA GPTSFAYQVE RSKFDEILLR
     NARRVGAEVH EGCSATDVIE DGDRVVGIRY TDDGGNRREA RASFVVDATG NKSRIYHRVG
     GTRQYSEFFR SLALFGYFEG GRRMPEPNRN NILCVAFDSG WFWYIPLSDT LTSVGAVVRS
     EMAEKVQGDS EQAMKALIEE CPMISDYLAP ARRVTTGQYG QLRVRKDYSY HQTTFWRPGM
     VLVGDAACFV DPVFSSGVHL ATYSALLAAR SINSVLAEIV DEKTAMQEFE ARYRRDYGVF
     YEFLVSFYEM HHSEDSYFWQ AKKVTGNSQP ELEAFVELIG GVSSGESALT DADALALRLQ
     ANTADFTTAV DALVANNSES MVPFMKSQVI RGVMHEGSQM QMRALLGEDA EPETPLFPGG
     LVSSADGMFW LPTDA
//