ID Q2JPQ7_SYNJB Unreviewed; 419 AA.
AC Q2JPQ7;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiE/T subunits {ECO:0000313|EMBL:ABD01225.1};
DE EC=2.1.1.132 {ECO:0000313|EMBL:ABD01225.1};
GN Name=cbiE {ECO:0000313|EMBL:ABD01225.1};
GN Synonyms=cbiT {ECO:0000313|EMBL:ABD01225.1};
GN OrderedLocusNames=CYB_0227 {ECO:0000313|EMBL:ABD01225.1};
OS Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium
OS Yellowstone B-Prime).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=321332 {ECO:0000313|EMBL:ABD01225.1, ECO:0000313|Proteomes:UP000001938};
RN [1] {ECO:0000313|EMBL:ABD01225.1, ECO:0000313|Proteomes:UP000001938}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JA-2-3B'a(2-13) {ECO:0000313|Proteomes:UP000001938};
RX PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA Bhaya D., Grossman A.R., Steunou A.S., Khuri N., Cohan F.M., Hamamura N.,
RA Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT "Population level functional diversity in a microbial community revealed by
RT comparative genomic and metagenomic analyses.";
RL ISME J. 1:703-713(2007).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; CP000240; ABD01225.1; -; Genomic_DNA.
DR RefSeq; WP_011431894.1; NC_007776.1.
DR AlphaFoldDB; Q2JPQ7; -.
DR STRING; 321332.CYB_0227; -.
DR KEGG; cyb:CYB_0227; -.
DR eggNOG; COG2241; Bacteria.
DR eggNOG; COG2242; Bacteria.
DR HOGENOM; CLU_031955_1_2_3; -.
DR OrthoDB; 9780707at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000001938; Chromosome.
DR GO; GO:0046025; F:precorrin-6Y C5,15-methyltransferase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11644; Precorrin-6Y-MT; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR012818; CbiE.
DR InterPro; IPR006365; Cbl_synth_CobL.
DR InterPro; IPR014008; Cbl_synth_MTase_CbiT.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR NCBIfam; TIGR02467; CbiE; 1.
DR NCBIfam; TIGR02469; CbiT; 1.
DR PANTHER; PTHR43182; COBALT-PRECORRIN-6B C(15)-METHYLTRANSFERASE (DECARBOXYLATING); 1.
DR PANTHER; PTHR43182:SF1; COBALT-PRECORRIN-7 C(5)-METHYLTRANSFERASE; 1.
DR Pfam; PF05175; MTS; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR PIRSF; PIRSF036428; CobL; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
PE 4: Predicted;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ABD01225.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001938};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABD01225.1}.
FT DOMAIN 42..193
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
FT DOMAIN 254..315
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 419 AA; 45561 MW; 83D49355C73830C2 CRC64;
MATAAPGRSP QLAVVGVAGD GSVASWGIPP LSQARVLAGA PHLLRHFTDH PARKIPLTGP
VESWIPLLQQ EMAQGSLVLL ASGDPLFFGI GRLLTEYFPA ERLAFYPQVS SVQLALNRLQ
IPWQEATILS LHGRGVERLE AVLKQGSPVI VVLTDPEHTP TVLAQFIADL RLPVRYQAWV
CSQLGSPQEQ VVPLQEGEDA VFPSPNVVVL RRVEPEPDPH RWPLVGIPDD QFYTFPDQPG
LITKQPIRLL TLGSLQLPQE GVVWDIGAGT GSVAIEIARL SSRLQVYAVE RNAMGICLIR
RNRQRFGPEN LQVIPGAAPQ VLADLPDPDR VVLGGGGKGI RDLLPVVGAR LRPGGILVAN
FATLETCSEA LQWLRSRGWQ VRVDHVQISR SAVLAEGTRF APLNPVYLLQ GIPSNWKAQ
//
