ID Q2JZW3_RHIEC Unreviewed; 984 AA.
AC Q2JZW3;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Sarcosine oxidase alpha subunit protein {ECO:0000313|EMBL:ABC93861.1};
GN Name=soxAe {ECO:0000313|EMBL:ABC93861.1};
GN OrderedLocusNames=RHE_PE00426 {ECO:0000313|EMBL:ABC93861.1};
OS Rhizobium etli (strain CFN 42 / ATCC 51251).
OG Plasmid p42e {ECO:0000313|EMBL:ABC93861.1,
OG ECO:0000313|Proteomes:UP000001936}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC93861.1, ECO:0000313|Proteomes:UP000001936};
RN [1] {ECO:0000313|EMBL:ABC93861.1, ECO:0000313|Proteomes:UP000001936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT seven interacting replicons.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CP000137; ABC93861.1; -; Genomic_DNA.
DR RefSeq; WP_011428279.1; NC_007765.1.
DR AlphaFoldDB; Q2JZW3; -.
DR KEGG; ret:RHE_PE00426; -.
DR HOGENOM; CLU_011963_0_0_5; -.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000001936; Plasmid p42e.
DR GO; GO:0008115; F:sarcosine oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR042204; 2Fe-2S-bd_N.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR006277; Sarcosine_oxidase_asu.
DR InterPro; IPR041117; SoxA_A3.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR01372; soxA; 1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF12831; FAD_oxidored; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR Pfam; PF17806; SO_alpha_A3; 1.
DR PIRSF; PIRSF037980; SoxA; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Plasmid {ECO:0000313|EMBL:ABC93861.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001936}.
FT DOMAIN 498..581
FT /note="SoxA A3"
FT /evidence="ECO:0000259|Pfam:PF17806"
FT DOMAIN 597..863
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 890..976
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 984 AA; 104537 MW; 6D5CA6E9EB8A4EC1 CRC64;
MTSFRLSSGG RIDRATTLGF SFDGKALEGH PGDTLASALL ANGIKLVGRS FKYHRPRGIL
TAGAAEPNAL VTIGSGGRTE PNTRATMIEL YGGLAAKSQN RWPSLGFDVG AVNGLLAPFL
SAGFYYKTFM WPAALWEKLY EPVIRKAAGL GRASYEADPD AYEKCWAHCD LLVIGAGPAG
LAAALTAGRA GARVILADEG SELGGSLLSD SGAVDGEPAD ALLGELLAEL EGLANVRRLP
RTTVFGWYDD NVFGALERVQ KHVAMPDPDR PVERLWRIVA RQAILATGAE ERPLVFGGND
IPGVMMAGAM RSYLNRQAVA PGQSTVIFTT NDTGYDTAAD LEAASLRVAA IVDSRADGGK
SWQGRAEVLK GARVIDAFGG KRLRGVSVGT EDGVRRIEAD ALAMSGGWSP IIHLACHRGG
KPHWSHETAA FLAPAAQDGL AITGSAAGLA QTAACLGDGA GKAAAALKAI GLAAEPAFAS
ATETAQRTKP LWSVKGSKGK AFVDYQNDVH LKDLGLAMRE GYGHVELAKR YTTSGMATDQ
GKLSNINAIG ILAEARGVSP AEVGTTTFRP FYTPVSFGAL TGASRGKDFQ PARKSPLHGW
AEKNGAVFVE TGLWYRSSWF PRAGEATWRD SVDREVLNIR KNAGLCDVST LGKIEIFGRD
AATFLDRVYC NGFAKLAVGK ARYGIMLRED GFIYDDGTTS RFSDEHFFMT TTTALAAGVL
THLEFCAQTL WPELDVCFAS STDQWAQMAV AGPKSRAILA EIVDEDISDA AFPFMSAREI
SLFGGRLEGR LFRISFSGER AYELAVPAGY GESVADAIMA AGEKHGICAY GAEALGVLRI
EKGHVTHAEI NGTVTPGDLG FGRMVSTTKL DFIGKAMLAR EGLQDPERPR LVGVMPLNPA
SSFRTGSHIL AEGAAATLEN DQGYVTSSAF SPTLGHKIGL ALVRRGPERI GEKVTVWNGL
HNEYTDAVLC QPVFIDPENE KLHA
//
