ID   Q2K4S9_RHIEC            Unreviewed;       776 AA.
AC   Q2K4S9;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   27-MAR-2024, entry version 108.
DE   SubName: Full=Pyrroloquinoline-quinone-dependent quinate dehydrogenase protein {ECO:0000313|EMBL:ABC92157.1};
DE            EC=1.1.5.2 {ECO:0000313|EMBL:ABC92157.1};
GN   OrderedLocusNames=RHE_CH03394 {ECO:0000313|EMBL:ABC92157.1};
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC92157.1, ECO:0000313|Proteomes:UP000001936};
RN   [1] {ECO:0000313|EMBL:ABC92157.1, ECO:0000313|Proteomes:UP000001936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT   seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC   -!- COFACTOR:
CC       Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC         Evidence={ECO:0000256|ARBA:ARBA00001931};
CC   -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00008156}.
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DR   EMBL; CP000133; ABC92157.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2K4S9; -.
DR   KEGG; ret:RHE_CH03394; -.
DR   eggNOG; COG4993; Bacteria.
DR   HOGENOM; CLU_018478_1_0_5; -.
DR   Proteomes; UP000001936; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0008876; F:quinoprotein glucose dehydrogenase activity; IEA:UniProtKB-EC.
DR   CDD; cd10280; PQQ_mGDH; 1.
DR   Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 2.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR017511; PQQ_mDH.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   NCBIfam; TIGR03074; PQQ_membr_DH; 1.
DR   PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR   PANTHER; PTHR32303:SF4; QUINOPROTEIN GLUCOSE DEHYDROGENASE; 1.
DR   Pfam; PF01011; PQQ; 3.
DR   SMART; SM00564; PQQ; 5.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:ABC92157.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001936};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          497..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   776 AA;  84472 MW;  61B42CEE5FE75941 CRC64;
     MRKTMKFLAA LFCFVLAFIG LGLMGGGALL LSLGGSPYYA ITGLAYLVAA VVLWRRKPLG
     ALIILLVAVF TLPWALWESG TNFWGLFARL MSPIALAGFA FVFAPARLPT AGRKLFHRGA
     VLAAILFAAG FGLAFIPHEV IRPSADTPAY KTVKGDNSPS DWTSYGRSTA GDRYSPFDQI
     NRSNVAQLDL AWTYRTGRGD GVDQNTPLQI GDTVYTCTPT NVITALDADT GKLRWTFDPK
     ASAPYWQRCR GLGYYRMPEQ DRLADDLCNE RLIQTTIDAR LLAIDSKTGA PCTAFGDNGT
     VQLSQGMGEV KTGYYFQTSA PLIARNLIVI GGWVTDNQEV GEPSGVIRAF NVVTGELEWA
     WDLGNPAITK LPPQGQTYTR ATPNMWTTAA FDDKLGLIYA PLGNTTPDYY GANRPAFADQ
     YNATLVALDV TTGRERWKFQ TVHHDIWDYD LPAQPVLIDL PDGNGAAVPA ILQTTKRGQL
     FLLNRQTGLP LAEVQEKPVP QTGGAPEEKL SPTQPYSVGM PTIGAERLTE QRAWGLTMFD
     QLACRIAFRK MRYDGDFTPI GTHPALQQPG NLGGLNWGSV SVDLSNNRVF MNDIRVPSIF
     ALVPRADYVD FALVTTAHGP SAPQRGTPYG MTTEKWTSRL RIPCTQPPWG TVTAVDLNTR
     KIAWQVPAGT AEQLGPFKIK MNLPMSMGLP TYAGTSTTAG GVVFFAGFQD YYIRAYDAEN
     GNELWKHPLP VGSSATPMTY ISPKTGKQYV LVSVGGAANS TDVGDYVLAF SLKDGD
//