ID Q2KCD4_RHIEC Unreviewed; 695 AA.
AC Q2KCD4;
DT 07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT 07-MAR-2006, sequence version 1.
DT 27-MAR-2024, entry version 102.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:ABC89502.1};
GN OrderedLocusNames=RHE_CH00686 {ECO:0000313|EMBL:ABC89502.1};
OS Rhizobium etli (strain CFN 42 / ATCC 51251).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=347834 {ECO:0000313|EMBL:ABC89502.1, ECO:0000313|Proteomes:UP000001936};
RN [1] {ECO:0000313|EMBL:ABC89502.1, ECO:0000313|Proteomes:UP000001936}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFN 42 / ATCC 51251 {ECO:0000313|Proteomes:UP000001936};
RX PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT seven interacting replicons.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP000133; ABC89502.1; -; Genomic_DNA.
DR RefSeq; WP_011424050.1; NC_007761.1.
DR AlphaFoldDB; Q2KCD4; -.
DR KEGG; ret:RHE_CH00686; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_5; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000001936; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:ABC89502.1};
KW Cilium {ECO:0000313|EMBL:ABC89502.1};
KW Flagellum {ECO:0000313|EMBL:ABC89502.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000001936};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 19..37
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 106..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 207..228
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 248..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 285..302
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 695 AA; 75749 MW; D370D9255C4C669E CRC64;
MAQPPALPLP KVAPSLRDIG FALGIIGIIC ILFLPIPPFL IDMGLAFSIA FSVLILMVAL
WIQKPLDFSS FPTILLIATM TRLALNIATT RVILSHGNEG HDAAGGVIAG FASLVMSGDF
VIGLIVFLIL ITINFIVITK GATRIAEVGA RFTLDAIPGK QMSIDADLSA GIIDEKEAQR
RRRELEEESS FFGAMDGASK FVRGDAVAGL IITAINVFGG IIIGYFRHGM PIGEAADVFV
KLSVGDGLVS QMPALIVSLA AGLLVSRGGT TGSTDQAVVN QLSGYPRALS VSAVLMFVLG
LMPGLPTIPF TVLGGLLAFG AWFIPRQVEA ENKLRREQEE KKVVQSKELE KDSVKSVLRT
SEIELALGKM VSTRLLGAHQ ELAFRVGKMR KKFATQYGFV VPEIKVTDDI AIAEKSYQIR
IHGTTVASNL LRVGEVLVVT GAGRKPSIPG DEIREPAFGM PAVSILENFA DDLKREGFQP
IDNVSVVLTH MSEVIRNNLP QLLSYKDVKV LIDRLDPEYK KLADEICSSH MSYSGLQAVL
KLLLAERVSI RNLHLILEAV AELAPHVRKT EQIVEHVRIR MAQQLCGDLA DNGVLRVLRL
GSKWDLAFHQ ALKRDAKGEV IEFDIDPRSL EEFSEQASKV IREFMDRGLP FALVTSPETR
SYVRMIIERL FATLPVLSHV ELAKGIEIKI LGSIS
//
