GenomeNet

Database: UniProt
Entry: Q2LMP0
LinkDB: Q2LMP0
Original site: Q2LMP0 
ID   XY11A_BOTFU             Reviewed;         227 AA.
AC   Q2LMP0;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2006, sequence version 1.
DT   05-DEC-2018, entry version 54.
DE   RecName: Full=Endo-1,4-beta-xylanase 11A;
DE            Short=Xylanase 11A;
DE            EC=3.2.1.8;
DE   AltName: Full=1,4-beta-D-xylan xylanohydrolase 11A;
DE   Flags: Precursor;
GN   Name=xyn11A;
OS   Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=40559;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], INDUCTION, FUNCTION, AND DISRUPTION
RP   PHENOTYPE.
RC   STRAIN=SAS56;
RX   PubMed=16404950; DOI=10.1094/MPMI-19-0025;
RA   Brito N., Espino J.J., Gonzalez C.;
RT   "The endo-beta-1,4-xylanase xyn11A is required for virulence in
RT   Botrytis cinerea.";
RL   Mol. Plant Microbe Interact. 19:25-32(2006).
CC   -!- FUNCTION: Endo-1,4-beta-xylanase involved in the hydrolysis of
CC       xylan, a major structural heterogeneous polysaccharide found in
CC       plant biomass representing the second most abundant polysaccharide
CC       in the biosphere, after cellulose. Required for planr infection
CC       and the appearance of secondary lesions.
CC       {ECO:0000269|PubMed:16404950}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in
CC         xylans.; EC=3.2.1.8;
CC   -!- PATHWAY: Glycan degradation; xylan degradation.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- INDUCTION: Expression is maximal when xylan is the only carbon
CC       source, and repressed by glucose. Expression is detected from the
CC       beginning of tomato leaves infection in the just-inoculated
CC       leaves, and the level sof transcript increased between 24 and 48 h
CC       postinfection simultaneously with the appearance of visible
CC       lesions on the leaves. {ECO:0000269|PubMed:16404950}.
CC   -!- DISRUPTION PHENOTYPE: Leads to reduced ability to infect tomato
CC       leaves or grape berries. {ECO:0000269|PubMed:16404950}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 11 (cellulase G)
CC       family. {ECO:0000305}.
DR   EMBL; DQ057980; AAZ03776.1; -; Genomic_DNA.
DR   ProteinModelPortal; Q2LMP0; -.
DR   SMR; Q2LMP0; -.
DR   CAZy; GH11; Glycoside Hydrolase Family 11.
DR   mycoCLAP; XYN11A_BOTFU; -.
DR   BRENDA; 3.2.1.8; 918.
DR   UniPathway; UPA00114; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0031176; F:endo-1,4-beta-xylanase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   GO; GO:0045493; P:xylan catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.60.120.180; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR013319; GH11/12.
DR   InterPro; IPR018208; GH11_AS_1.
DR   InterPro; IPR033119; GH11_AS_2.
DR   InterPro; IPR033123; GH11_dom.
DR   InterPro; IPR001137; Glyco_hydro_11.
DR   Pfam; PF00457; Glyco_hydro_11; 1.
DR   PRINTS; PR00911; GLHYDRLASE11.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS00776; GH11_1; 1.
DR   PROSITE; PS00777; GH11_2; 1.
DR   PROSITE; PS51761; GH11_3; 1.
PE   2: Evidence at transcript level;
KW   Carbohydrate metabolism; Glycosidase; Hydrolase;
KW   Polysaccharide degradation; Secreted; Signal; Virulence;
KW   Xylan degradation.
FT   SIGNAL        1     19       {ECO:0000255}.
FT   CHAIN        20    227       Endo-1,4-beta-xylanase 11A.
FT                                /FTId=PRO_5000140289.
FT   DOMAIN       37    227       GH11. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01097}.
FT   ACT_SITE    122    122       Nucleophile. {ECO:0000255|PROSITE-
FT                                ProRule:PRU10062}.
FT   ACT_SITE    214    214       Proton donor. {ECO:0000255|PROSITE-
FT                                ProRule:PRU10063}.
SQ   SEQUENCE   227 AA;  23824 MW;  F4969A37C3A9B887 CRC64;
     MVSASSLLLA ASAIAGVFSA PAAAPVSENL NVLQERALTS SATGTSGGYY YSFWTDGSGG
     VTYSNGANGQ YAVSWTGNKG NFVGGKGWAV GSERSISYTG SYKPNGNSYL SVYGWTTSPL
     IEYYIVEDFG TYDPSSAATE IGSVTSDGST YKILETTRTN QPSVQGTATF KQYWSVRTSK
     RTSGTVTTAN HFAAWKKLGL TLGSTYNYQI VAVEGYQSSG SASITVS
//
DBGET integrated database retrieval system