ID Q2LSE4_SYNAS Unreviewed; 357 AA.
AC Q2LSE4;
DT 21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 21-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Mannose-1-phosphate guanylyltransferase {ECO:0000313|EMBL:ABC77001.1};
DE EC=2.7.7.22 {ECO:0000313|EMBL:ABC77001.1};
GN ORFNames=SYN_01031 {ECO:0000313|EMBL:ABC77001.1};
OS Syntrophus aciditrophicus (strain SB).
OC Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC Syntrophus.
OX NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC77001.1, ECO:0000313|Proteomes:UP000001933};
RN [1] {ECO:0000313|EMBL:ABC77001.1, ECO:0000313|Proteomes:UP000001933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB {ECO:0000313|EMBL:ABC77001.1,
RC ECO:0000313|Proteomes:UP000001933};
RX PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA Campbell J.W., Gunsalus R.P.;
RT "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT of microbial growth.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
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DR EMBL; CP000252; ABC77001.1; -; Genomic_DNA.
DR RefSeq; WP_011417030.1; NC_007759.1.
DR AlphaFoldDB; Q2LSE4; -.
DR STRING; 56780.SYN_01031; -.
DR KEGG; sat:SYN_01031; -.
DR eggNOG; COG0836; Bacteria.
DR HOGENOM; CLU_035527_0_1_7; -.
DR InParanoid; Q2LSE4; -.
DR OrthoDB; 9806359at2; -.
DR Proteomes; UP000001933; Chromosome.
DR GO; GO:0008928; F:mannose-1-phosphate guanylyltransferase (GDP) activity; IEA:UniProtKB-EC.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0005976; P:polysaccharide metabolic process; IEA:InterPro.
DR CDD; cd02509; GDP-M1P_Guanylyltransferase; 1.
DR InterPro; IPR049577; GMPP_N.
DR InterPro; IPR001538; Man6P_isomerase-2_C.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR Pfam; PF01050; MannoseP_isomer; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF159283; Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ABC77001.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001933};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABC77001.1}.
FT DOMAIN 3..284
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 315..353
FT /note="Mannose-6-phosphate isomerase type II C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01050"
SQ SEQUENCE 357 AA; 39343 MW; 3D29F3FAFF978470 CRC64;
MYAVIMAGGK GARFWPRSRE HKPKHLLDIT GTRTIIQETV SRISSLIPPD RTLIITGAAH
ADELRRQLPE IPAENILVEP VGRNTAPCIG LAAIHIRRRA GDAVMAVLPS DHVIADDRVF
LDTLAAAAEA AEREDALVTI GIKPTGPETG YGYIERGNPV GQIGGKLIYG VWSIREKPPL
EQAMSFVEAG TFYWNSGMFI WKTSTILQAI ETHLPDLHAG LLRLEAALGT EQYEVVLRDT
YEETRSISID YGVMEKADKV LVIPGNFAWS DVGSWDALWE FLEKDFAGNA CRGEVIAVES
ADSLVYSPKK LVALVGVRDL IVVETDDALL ICRRGDSQKV KSIVDILEEK NLKNYLE
//
