ID Q2LSH5_SYNAS Unreviewed; 939 AA.
AC Q2LSH5;
DT 21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 21-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Sensory domain linked to a LuxR family regulatory protein {ECO:0000313|EMBL:ABC77037.1};
GN ORFNames=SYN_00112 {ECO:0000313|EMBL:ABC77037.1};
OS Syntrophus aciditrophicus (strain SB).
OC Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC Syntrophus.
OX NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC77037.1, ECO:0000313|Proteomes:UP000001933};
RN [1] {ECO:0000313|EMBL:ABC77037.1, ECO:0000313|Proteomes:UP000001933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB {ECO:0000313|EMBL:ABC77037.1,
RC ECO:0000313|Proteomes:UP000001933};
RX PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA Campbell J.W., Gunsalus R.P.;
RT "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT of microbial growth.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
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DR EMBL; CP000252; ABC77037.1; -; Genomic_DNA.
DR RefSeq; WP_011417066.1; NC_007759.1.
DR AlphaFoldDB; Q2LSH5; -.
DR STRING; 56780.SYN_00112; -.
DR KEGG; sat:SYN_00112; -.
DR eggNOG; COG2197; Bacteria.
DR eggNOG; COG2202; Bacteria.
DR eggNOG; COG4936; Bacteria.
DR HOGENOM; CLU_312358_0_0_7; -.
DR InParanoid; Q2LSH5; -.
DR OrthoDB; 9778628at2; -.
DR Proteomes; UP000001933; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR018771; PocR_dom.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00196; GerE; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 3.
DR Pfam; PF10114; PocR; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SMART; SM00086; PAC; 4.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
DR PROSITE; PS50113; PAC; 4.
DR PROSITE; PS50112; PAS; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001933}.
FT DOMAIN 244..299
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 318..370
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 410..479
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 484..536
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 537..608
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 611..663
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 664..705
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 738..790
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 873..938
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT COILED 361..406
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 939 AA; 107328 MW; 21605B07DBFB80EC CRC64;
MKNKNKTKVQ LANEFEEMRM RMMKLESGEA HHMQAEFCKE TLRQSILSLE VDTGAPGIAD
ILDAPMIESL MNSFHEFTHI PLAIVDLRGK VLAGPGWGDI CKRFHRVHPD TCRNCIESDI
LLSAGIPAGE YKLYKCKNNM WDIATPIIVD GKHLGNVISG QFFFDDESVD YELFRLQAKK
YGFPEKEYIA ALEAVPRFSR KSMDAGMTFL MKLARMISQM SYSNIKLVQS LEERETLMKS
VLAAEDKYRG IFENALEGIY RITTSGRFLD ANPALAHIFG YDTPEALINA VTPVGELLHV
DPQSREQFIA IMDQQDYATY EGKMLKKDGS PFWIHLRGRA VRDAEGKTIH YEGFAEDITE
KKKIDEELKH YRDDLEAMVT ERTFQLQEKN RQLISEIAER KRVEEALSKN EALYRNLFEN
IPIGMFQTNF EEGGFISVNP AYAKILGYES PEDLKSSVAN VAKIHVDPKD RDTILAALRD
RDWYHAEYPR LRKDGSVMIG KVAIRSVLKA DGSVDYIEGI VEDVTERRLA EEKLKKYAEE
VTDLYENAPC GYHSLAKDGT IIRINNTELT WLGYSREEVV GKMKFTDLIP PDESASFWQT
FPLLQKQGRV SNIEGKLTRR DGSILPVLIN ATTIFDENGN FLMSRSSVFD NTERKKIEDA
LVENEVLYRN LFENASIGMF QSTLEGQFIR INKAYATMLG YDSPEEVIST ITDTSTQIHT
DPENRTKLLA ALKQEGWCYA EQPYLRKDGT IMIAELAVRK VTGQDGAISY LEGIVEDITK
WKKAEEALMK SERELRIKAH NLLEVNTTMK VLLDTMERDQ EELKERILTN IKEQVLPWLE
KLKKRPLQDV EKDYIQMAES QLAEIASPFI HKLTSSFLNL TKKEIQVASL VREGKTSKEI
AELLNSKKRV IDFHRENIRK KLGLNNKKGS LAILLRSFS
//
