ID Q2LWD2_SYNAS Unreviewed; 487 AA.
AC Q2LWD2;
DT 21-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 21-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Transmembrane symporter {ECO:0000313|EMBL:ABC78391.1};
GN ORFNames=SYN_00846 {ECO:0000313|EMBL:ABC78391.1};
OS Syntrophus aciditrophicus (strain SB).
OC Bacteria; Thermodesulfobacteriota; Syntrophia; Syntrophales; Syntrophaceae;
OC Syntrophus.
OX NCBI_TaxID=56780 {ECO:0000313|EMBL:ABC78391.1, ECO:0000313|Proteomes:UP000001933};
RN [1] {ECO:0000313|EMBL:ABC78391.1, ECO:0000313|Proteomes:UP000001933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SB {ECO:0000313|EMBL:ABC78391.1,
RC ECO:0000313|Proteomes:UP000001933};
RX PubMed=17442750; DOI=10.1073/pnas.0610456104;
RA McInerney M.J., Rohlin L., Mouttaki H., Kim U., Krupp R.S.,
RA Rios-Hernandez L., Sieber J., Struchtemeyer C.G., Bhattacharyya A.,
RA Campbell J.W., Gunsalus R.P.;
RT "The genome of Syntrophus aciditrophicus: life at the thermodynamic limit
RT of microbial growth.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:7600-7605(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC DIT1 subfamily. {ECO:0000256|ARBA:ARBA00007349}.
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DR EMBL; CP000252; ABC78391.1; -; Genomic_DNA.
DR RefSeq; WP_011418410.1; NC_007759.1.
DR AlphaFoldDB; Q2LWD2; -.
DR STRING; 56780.SYN_00846; -.
DR KEGG; sat:SYN_00846; -.
DR eggNOG; COG0471; Bacteria.
DR HOGENOM; CLU_005170_11_0_7; -.
DR InParanoid; Q2LWD2; -.
DR OrthoDB; 9763713at2; -.
DR Proteomes; UP000001933; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR030676; CitT-rel.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR42826:SF3; DICARBOXYLATE TRANSPORTER 1, CHLOROPLASTIC; 1.
DR PANTHER; PTHR42826; DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001933};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 190..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 418..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 487 AA; 52917 MW; 1772F8D38E42F426 CRC64;
MIDRKMLGVI AIAVLGILIA LVQPFAPGLS PLGHYVMGTV IAGLGMWIFR PGNLPFMSGT
SIILGLTLAL FFAYKAGLVF PGKVPFKAPP QIYGVVMGGF TSSAVWVLIP ALYFGFVLQK
TGLGKRIAYM VLKTFPATWL GLAISWLVIG VALSALTPSI TVRVAIVVPI AIGIVEACKL
EYRSKGSAYI CLLAWGMALF PGTGWLTGSL SGPIMQGFFP PEIKHLCNFD DWFKILALPW
FVVTFVYVAL AYILARPKEA IAISSDVFKE EYKKLGPMSK DEIISLLILV GSLLMFFTEK
QHGIPTAATA LFALFLFVMF RIIAGPEISS GINWDVVCFF GIAVALPPIF GVSGISAWFG
PLIKGPIMSI AGAPLLFMLV ITAGLMLIRF IDVPWGFTTA ALTIIMLIPL FNDFGYHPLA
VTMAYLIAVN FFLLSYQQPF ILMGEGMIQG KGWAPAHVFK FGLIYIVAAF ISLLVAVPYW
KMIGVIR
//
