ID Q2NGJ0_METST Unreviewed; 226 AA.
AC Q2NGJ0;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=F420H2:NADP oxidoreductase {ECO:0000313|EMBL:ABC57063.1};
DE EC=1.6.-.- {ECO:0000313|EMBL:ABC57063.1};
GN Name=fno {ECO:0000313|EMBL:ABC57063.1};
GN OrderedLocusNames=Msp_0665 {ECO:0000313|EMBL:ABC57063.1};
OS Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS MCB-3).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX NCBI_TaxID=339860 {ECO:0000313|EMBL:ABC57063.1, ECO:0000313|Proteomes:UP000001931};
RN [1] {ECO:0000313|EMBL:ABC57063.1, ECO:0000313|Proteomes:UP000001931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3
RC {ECO:0000313|Proteomes:UP000001931};
RX PubMed=16385054; DOI=10.1128/JB.188.2.642-658.2006;
RA Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA Gottschalk G., Thauer R.K.;
RT "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT intestinal archaeon is restricted to methanol and H2 for methane formation
RT and ATP synthesis.";
RL J. Bacteriol. 188:642-658(2006).
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DR EMBL; CP000102; ABC57063.1; -; Genomic_DNA.
DR RefSeq; WP_011406263.1; NC_007681.1.
DR AlphaFoldDB; Q2NGJ0; -.
DR STRING; 339860.Msp_0665; -.
DR GeneID; 41325240; -.
DR KEGG; mst:Msp_0665; -.
DR eggNOG; arCOG00457; Archaea.
DR HOGENOM; CLU_076368_1_0_2; -.
DR OrthoDB; 8635at2157; -.
DR Proteomes; UP000001931; Chromosome.
DR GO; GO:0070967; F:coenzyme F420 binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR GO; GO:0006740; P:NADPH regeneration; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR010185; NpdG.
DR InterPro; IPR028939; P5C_Rdtase_cat_N.
DR NCBIfam; TIGR01915; npdG; 1.
DR PANTHER; PTHR14239; DUDULIN-RELATED; 1.
DR PANTHER; PTHR14239:SF0; F420-DEPENDENT NADP REDUCTASE; 1.
DR Pfam; PF03807; F420_oxidored; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:ABC57063.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001931}.
FT DOMAIN 2..102
FT /note="Pyrroline-5-carboxylate reductase catalytic N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF03807"
SQ SEQUENCE 226 AA; 24337 MW; F99F7AF0F245B26D CRC64;
MKISIIGGTG SQGLNLGKRF AIAGEDVIIG SRKEEKALTK VEECLDLLKD YDNIKMEGMS
NEDAAKAGDL LILTVPLSAQ KPTLQSIKDF VGDKIVLDAT VPLETAIGGS PARFIDLMEG
SAAERTAKIL KKTDAKVIAA FNNISNSLLE NIPEPIDCDC LIAGNDNEAK KIAIELIEKI
PGVECIDCGK LEKARMIEKI TPLLIGLNIK YKSHYGGLRI TGISRE
//
