ID Q2NH84_METST Unreviewed; 235 AA.
AC Q2NH84;
DT 07-FEB-2006, integrated into UniProtKB/TrEMBL.
DT 07-FEB-2006, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=CRISPR associated protein Cas6 C-terminal domain-containing protein {ECO:0000259|Pfam:PF01881};
GN OrderedLocusNames=Msp_0418 {ECO:0000313|EMBL:ABC56819.1};
OS Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS MCB-3).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX NCBI_TaxID=339860 {ECO:0000313|EMBL:ABC56819.1, ECO:0000313|Proteomes:UP000001931};
RN [1] {ECO:0000313|EMBL:ABC56819.1, ECO:0000313|Proteomes:UP000001931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3
RC {ECO:0000313|Proteomes:UP000001931};
RX PubMed=16385054; DOI=10.1128/JB.188.2.642-658.2006;
RA Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA Gottschalk G., Thauer R.K.;
RT "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT intestinal archaeon is restricted to methanol and H2 for methane formation
RT and ATP synthesis.";
RL J. Bacteriol. 188:642-658(2006).
CC -!- SIMILARITY: Belongs to the CRISPR-associated protein Cas6/Cse3/CasE
CC family. {ECO:0000256|ARBA:ARBA00005937}.
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DR EMBL; CP000102; ABC56819.1; -; Genomic_DNA.
DR RefSeq; WP_011406019.1; NC_007681.1.
DR AlphaFoldDB; Q2NH84; -.
DR STRING; 339860.Msp_0418; -.
DR GeneID; 41324993; -.
DR KEGG; mst:Msp_0418; -.
DR eggNOG; arCOG04342; Archaea.
DR HOGENOM; CLU_089858_1_0_2; -.
DR OrthoDB; 43942at2157; -.
DR Proteomes; UP000001931; Chromosome.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd21140; Cas6_I-like; 1.
DR Gene3D; 3.30.70.1890; -; 1.
DR Gene3D; 3.30.70.1900; -; 1.
DR InterPro; IPR049435; Cas_Cas6_C.
DR InterPro; IPR010156; CRISPR-assoc_prot_Cas6.
DR InterPro; IPR045747; CRISPR-assoc_prot_Cas6_N_sf.
DR NCBIfam; TIGR01877; cas_cas6; 1.
DR PANTHER; PTHR36984; CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1; 1.
DR PANTHER; PTHR36984:SF1; CRISPR-ASSOCIATED ENDORIBONUCLEASE CAS6 1; 1.
DR Pfam; PF01881; Cas_Cas6_C; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Reference proteome {ECO:0000313|Proteomes:UP000001931};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 113..232
FT /note="CRISPR associated protein Cas6 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01881"
SQ SEQUENCE 235 AA; 28131 MW; A8A9748E3E8CBDD5 CRC64;
MRLIIKFNPL SDCKYDAIGK YDIQGFIYSL LKDTEFKNYH DIKGFKFFTF SNIFPVCDFK
QDNLKTIIIS SPSSAFIKVL YYQLSNLEIF RLNKYYMEKY KVKLIKNNKC SNSIITGTPI
VLFENNYENR YYSFNQKLDF NFFFNRLKEN ALKKYTAYTQ DEINLESDLF DSFEFNREVS
MRIIMKNQTF IIIGSLWKVL EKNIAREDRK FYNFLFDCGL GEKNSLGMGF INNRR
//
